Results 41 to 50 of about 34,656 (117)

Determinação da permeabilidade ao ar em amostras indeformadas de solo pelo método da pressão decrescente Determination of air permeability in undisturbed soil samples by the decreasing pressure method

Revista Brasileira de Ciência do Solo, 2009
A permeabilidade do solo ao ar (Ka) determina o fluxo convectivo de gases na matriz do solo e a troca de gases na interface do sistema solo-atmosfera, influenciando diretamente a qualidade do ambiente físico para o crescimento de plantas e a taxa de ...
Álvaro Pires da Silva, Tairone Paiva Leão, Cássio Antonio Tormena, Antonio Carlos Andrade Gonçalves   +3 more
doaj   +1 more source

A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize

Frontiers in Physiology, 2019
Mdm2 and MdmX are related proteins serving in the form of the Mdm2 homodimer or Mdm2/MdmX heterodimer as an E3 ubiquitin ligase for the tumor suppressor p53.
Pavlína Kosztyu, Iva Slaninová, Barbora Valčíková, Barbora Valčíková, Amandine Verlande, Amandine Verlande, Petr Müller, Jan J. Paleček, Jan J. Paleček, Stjepan Uldrijan, Stjepan Uldrijan   +10 more
doaj   +1 more source

Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase

Scientific Reports, 2017
C-terminus of Hsc/p70-Interacting Protein (CHIP) is a homodimeric E3 ubiquitin ligase. Each CHIP monomer consists of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain.
Zhaofeng Ye, Patrick G. Needham, Samuel K. Estabrooks, Susan K. Whitaker, Brandon L. Garcia, Saurav Misra, Jeffrey L. Brodsky, Carlos J. Camacho   +7 more
doaj   +1 more source

Prostaglandin E2 receptor 3 signaling is induced in placentas with unexplained recurrent pregnancy losses

Endocrine Connections, 2018
Although an inflammatory microenvironment is required for successful implantation, an inflammatory overreaction is one of the causes of unexplained recurrent pregnancy losses (uRPL).
Yao Ye, Aurelia Vattai, Nina Ditsch, Christina Kuhn, Martina Rahmeh, Sven Mahner, Myriam Ripphahn, Roland Immler, Markus Sperandio, Udo Jeschke, Viktoria von Schönfeldt   +10 more
doaj   +1 more source

Somatic estrogen receptor α mutations that induce dimerization promote receptor activity and breast cancer proliferation

The Journal of Clinical Investigation
Physiologic activation of estrogen receptor α (ERα) is mediated by estradiol (E2) binding in the ligand-binding pocket of the receptor, repositioning helix 12 (H12) to facilitate binding of coactivator proteins in the unoccupied coactivator binding ...
Seema Irani, Wuwei Tan, Qing Li, Weiyi Toy, Catherine Jones, Mayur Gadiya, Antonio Marra, John A. Katzenellenbogen, Kathryn E. Carlson, Benita S. Katzenellenbogen, Mostafa Karimi, Ramya Segu Rajappachetty, Isabella S. Del Priore, Jorge S. Reis-Filho, Yang Shen, Sarat Chandarlapaty   +15 more
doaj   +1 more source

Assessing the Stress Induced by Novel Packaging in GaN HEMT Devices via Raman Spectroscopy

Applied Sciences
Micro-Raman spectroscopy was carried out to evaluate the localized residual stresses in commercial Gallium-Nitride-based devices, specifically, AlGaN/GaN high-electron-mobility Transistors (HEMTs) with a novel packaging design provided by ...
Zainab Dahrouch, Giuliana Malta, Moreno d’Ambrosio, Angelo Alberto Messina, Mattia Musolino, Alessandro Sitta, Michele Calabretta, Salvatore Patanè   +7 more
doaj   +1 more source

Interband optical transitions in the region of exciton resonances in In0.3Ga0.7As/GaAs quantum wells

Moldavian Journal of the Physical Sciences, 2012
Reflectance spectra of quantum wells (QWs) with 8-nm-thick In0.3Ga0.7As layers with a 9-nm-thick GaAs barrier layer up and a 100-nm-thick barrier layer down were investigated in the spectral range of 0.5–1.6 eV in S- and P- polarizations at an incidence ...
Sîrbu, Nicolae, Dorogan, Andrei, Dorogan, Valerian, Vieru, Tatiana, Ursachi, Veaceslav, Zalamai, Victor   +5 more
doaj  

The residue 86 of the Getah virus E2 glycoprotein mediates both glycosaminoglycan- and LDLR-dependent infection.

PLoS Pathogens
Getah virus (GETV), a mosquito-borne alphavirus, poses an emerging threat to public health with its increasingly broad host spectrum. While glycosaminoglycans (GAGs) serve as critical attachment factors for many alphaviruses and the low-density ...
Xiangshu Qiu, Rongguang Lu, Jiaxin Tian, He Zhang, Jiyong Zhou, Mengsi Sun, Xinyu Cao, Xiangyu Zhu, Bocheng Liu, Qihui Yu, Yuanyuan Li, Hualei Wang, Ningyi Jin, Huijun Lu, Ning Shi   +14 more
doaj   +1 more source

The UBE2/E2 ubiquitin-conjugating enzyme family at the interface of tumor biology and antitumor immunity: mechanisms, biomarkers, and therapeutic opportunities

Frontiers in Immunology
While the catalytic role of ubiquitin-conjugating (UBE2/E2) enzymes within the ubiquitin–proteasome system is well established, their substrate-specifying functions in cancer, particularly at the tumor–immune interface, remain comparatively underexplored.
Hai Zhao, Jiaxin Yang, Fan Yang
doaj   +1 more source

A novel missense variant at the site of interaction between RLIM and E2 ubiquitin-conjugating enzymes causes Tønne-Kalscheuer syndrome

BMC Pediatrics
Hemizygous variants in the RLIM gene, which is located on chromosome Xq13, cause Tønne-Kalscheuer syndrome (TOKAS). This X-linked recessive disorder is characterized by intellectual disability (ID), global developmental delay, behavioral impairment, gait
Evelina Siavrienė, Justas Dapkūnas, Živilė Maldžienė, Violeta Mikštienė, Gunda Petraitytė, Eglė Preikšaitienė   +5 more
doaj   +1 more source