Results 221 to 230 of about 109,331 (244)
The E3 ligases Itch and WWP2 regulate autoimmune neuroinflammation by controlling T<sub>H</sub>2 to T<sub>H</sub>17 cell conversion via interleukin-4-STAT5 axis in mice. [PDF]
Nat CommunZhao M +5 more
europepmc +1 more source
Animal Research and One Health, EarlyView.This study analyzed the spleen transcriptomes of different chicken breeds, identified key differentially expressed genes (EGR1, FOS, and DUSP1) that regulate resistance to Salmonella infection, and elucidated the underlying regulatory mechanisms, thereby providing new targets for disease‐resistant breeding in poultry.
Zixuan Wang +8 more
wiley +1 more source
ELiAH: the atlas of E3 ligases in human tissues for targeted protein degradation with reduced off-target effect. [PDF]
Database (Oxford)Paik H +6 more
europepmc +1 more source
E3 ligases: a ubiquitous link between DNA repair, DNA replication and human disease. [PDF]
Biochem JChauhan AS, Jhujh SS, Stewart GS.
europepmc +1 more source
Genetic retargeting of E3 ligases to enhance CAR T cell therapy. [PDF]
Cell Chem BiolLane IC +17 more
europepmc +1 more source
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C-degron mimicry confers E3 ligase selectivity
Nature Reviews Molecular Cell Biology, 2023Lisa Heinke
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Systemwide disassembly and assembly of SCF ubiquitin ligase complexes
Cell, 2023Brenda Schulman +2 more
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An engineered platform for reconstituting functional multisubunit SCF E3 ligase in vitro
Molecular Plant, 2022Mingjiang Chen
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SCF ubiquitin ligase-targeted therapies
Nature Reviews Drug Discovery, 2014Julia K Pagan +2 more
exaly