Results 161 to 170 of about 68,518 (300)

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth, Aleya Shedd, Ariel Aiken, Solmi Cheon, Josh Bandopadhay, Kiran Kaur, Kimberly M. Huber, Maria H. Chahrour   +7 more
wiley   +1 more source

Evolution, composition and functions of cullin E3 ubiquitin ligases in trypanosomes. [PDF]

Sci Rep
Del Pino RC, Zoltner M, Butterfield ER, Field MC.   +3 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase RNF43 [PDF]

, 2020
openaire   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

The multifaceted roles of E3 ubiquitin ligases in osteoarthritis. [PDF]

Front Cell Dev Biol
Jin Z, Zhu Z, Chen J, Jing X, Tan J, Zeng J.   +5 more
europepmc   +1 more source

E3 Ubiquitin-Protein Ligase NEDD4 [PDF]

, 2020
openaire   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control-associated E3 ubiquitin ligases LTN1 and RNF10. [PDF]

FEBS Lett
Huang Y, Hashimoto S, Ito S, Kikuguchi C, Hoshi M, Yamaguchi K, Furukawa Y, Suzuki T, Inada T.   +8 more
europepmc   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

The role of HECT-type E3 ubiquitin ligases in DNA damage response and repair. [PDF]

Cell Death Discov
Giovannini S, Fiorilli C, Moriconi V, Shi Y, Candi E, Melino G, Bernassola F.   +6 more
europepmc   +1 more source