Results 201 to 210 of about 47,588 (257)

A Functional Assay for Mining Noninhibitory Enzyme Ligands from One Bead One Compound Libraries: Application to E3 Ubiquitin Ligases. [PDF]

J Am Chem Soc
Gui W, Goss A, Kodadek T.
europepmc   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

Genome-wide identification and functional analysis of U-box E3 ubiquitin ligases gene family related to drought stress response in Musa acuminata. [PDF]

BMC Plant Biol
Wei Y, Zhang F, Wang C, Ma M, Yang Y, Yuan Y, Dou T, Zhang S, Huang X.   +8 more
europepmc   +1 more source

A proteomic investigation of forebrain regeneration in the leopard gecko (Eublepharis macularius)

Developmental Dynamics, EarlyView.
Our investigation reveals ontogenetic, injury‐ and regeneration‐associated proteomic changes in the leopard gecko forebrain. Abstract Background The ability to replace lost or damaged neurons following an injury is termed reactive neurogenesis. Although reactive neurogenesis has been reported in several lizard species, the molecular mechanisms ...
Alexandra I. Noble, Samantha L. Payne, Matthew K. Vickaryous   +2 more
wiley   +1 more source

A Novel Prognostic Signature of Mitophagy-Related E3 Ubiquitin Ligases in Breast Cancer. [PDF]

Int J Mol Sci
Bian K, Yang C, Zhang F, Huang L.
europepmc   +1 more source

The emerging role of E3 ubiquitin ligases and deubiquitinases in metabolic dysfunction-associated steatotic liver disease. [PDF]

J Transl Med
Zhang Y, Yang J, Min J, Huang S, Li Y, Liu S.   +5 more
europepmc   +1 more source

Redirecting E3 ubiquitin ligases for targeted protein degradation with heterologous recognition domains. [PDF]

J Biol Chem
Yang H, Zheng G, Li GY, Alshaye A, Orkin SH.   +4 more
europepmc   +1 more source

Radiation-induced nuclear translocation of NPRL2 hijacks E3 ubiquitin ligases to enhance DNA repair <i>via</i> the AMPK/WDR24 axis, contributing to CRC radioresistance. [PDF]

Acta Pharm Sin B
Wang X, Zhao Y, Yang X, Liu T, Zhou W, Niu S, Jin M, Chen Y, Liu RY, Bao Y, Yue X.   +10 more
europepmc   +1 more source

Chromatin-associated cullin-RING E3 ubiquitin ligases: keeping transcriptionally active NF-κB in check. [PDF]

Front Immunol
Gong M, Luo J, Liang Q, Liu Y, Zheng Y, Yang XD.   +5 more
europepmc   +1 more source

E3 Ubiquitin ligases Cbl-b and c-Cbl maintain the homeostasis of macrophages by regulating the M-CSF/M-CSFR signaling axis. [PDF]

Cell Death Dis
Xu F, Tan C, Tang K, Qiao G, Shao Y, Li X, Zhou J, Zhu P, Wu M, Cai J, Gao X, Wang Y, Huang B, Wang W, Xia T, Xu X, Li J, Chen Z, Shi Y, Hao C, Yang Y, Zhang J.   +21 more
europepmc   +1 more source