Results 41 to 50 of about 129,891 (225)
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The small splice variant of HPV16 E6, E6⁎, reduces tumor formation in cervical carcinoma xenografts [PDF]
, 2014 High-risk types of human papillomavirus (HPV) cause nearly all cases of cervical cancer. The E6 oncoprotein is produced as a full-length variant (E6) as well as several shorter isoforms (E6⁎).
Hong, Linda +7 more
core +1 more source
A Drosophila Model of HPV E6-Induced Malignancy Reveals Essential Roles for Magi and the Insulin Receptor. [PDF]
PLoS Pathogens, 2016 Cervical cancer is one of the leading causes of cancer death in women worldwide. The causative agents of cervical cancers, high-risk human papillomaviruses (HPVs), cause cancer through the action of two oncoproteins, E6 and E7.
Mojgan Padash Barmchi +5 more
doaj +1 more source
Advanced Functional Materials, EarlyView.This study advances SafeWax, a bio‐inspired, fatty‐acids‐based superhydrophobic coating, by identifying an agriculturally compliant solvent and revealing how solvent‐controlled Fatty acid crystallization governs the coating's microscopic structure and performance.
Niv Ben‐Arie +13 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2013 Aims: To examine molecular and metabolic consequences of HPV-16 viral- protein E6, which targets p53 for degradation, in A2780 (ovarian cancer) cells. Methods: Isogenic derivatives of A2780 cells, with empty-vector (E6-) or E6 (E6+) transfection, were ...
Yuen-Li Chung +5 more
doaj +1 more source
The E6AP binding pocket of the HPV16 E6 oncoprotein provides a docking site for a small inhibitory peptide unrelated to E6AP, indicating druggability of E6. [PDF]
PLoS ONE, 2014 The HPV E6 oncoprotein maintains the malignant phenotype of HPV-positive cancer cells and represents an attractive therapeutic target. E6 forms a complex with the cellular E6AP ubiquitin ligase, ultimately leading to p53 degradation.
Katia Zanier +8 more
doaj +1 more source
E6-mediated degradation of PDZ domain proteins is conserved in Drosophila.
, 2016 (A-T) apterous-Gal4 was used to express transgenes in the dorsal compartment of wing imaginal discs. In all images dorsal is to the left and ventral is to the right and dashed lines indicate the boundary between the two compartments.
Bing Zhang (129) +5 more
core +1 more source
Advanced Materials, EarlyView.A sulfur‐doped lignin‐derived carbon‐coated Ni‐NiO‐MoO2 nanorod array was synthesized, exhibiting enhanced UOR performance ‐ due to lattice‐strain and built‐in electric field effects by multiphase heterogeneous interface in Ni‐NiO‐MoO2@SC, excellent corrosion resistance, mass‐transport ability, and long‐term stability (500 mA cm−2 at 1.53 V for 500 h ...
Jiawei Li +9 more
wiley +1 more source
Structural insights into a wildtype domain of the oncoprotein E6 and its interaction with a PDZ domain. [PDF]
PLoS ONE, 2013 The high-risk human papilloma virus (HPV) oncoproteins E6 and E7 interact with key cellular regulators and are etiological agents for tumorigenesis and tumor maintenance in cervical cancer and other malignant conditions.
André Mischo +4 more
doaj +1 more source
Advanced Materials, EarlyView.Self‐invalidating multilayer physical unclonable functions (PUFs) integrate fingerprint‐like metal nanopattern bilayers from block copolymer templates with highly reactive reduced graphene oxide (rGO) interlayers. This tamper‐responsive architecture blocks all unauthorized physical and chemical replication attempts while autonomously deactivating ...
Gyu Hui Jo +7 more
wiley +1 more source