Results 81 to 90 of about 62,740 (215)

اثر تزریق سیستمیک dbcAMP بر پاسخ مهاجرتی سلول های بنیادی عصبی در مدل EAE بیماری ام اس [PDF]

مجله دانشگاه علوم پزشکی سبزوار, 1970
زمینه و هدف: افزایش مشارکت سلول های بنیادی عصبی در ترمیم اندوژن آسیب های میلینی یکی از مهم ترین استراتژی ها برای درمان های نوین بیماری ام اس است. افزایش cAMP با فعال کردن PKA و همچنین مستقل از آن، ظرفیت ترمیمی مغز را افزایش می دهد.
سعید سمنانیان, حسین بهاروند, شیوا خضری, محمد جوان   +3 more
doaj  

Caerulomycin A suppresses the differentiation of naïve T cells and alleviates the symptoms of experimental autoimmune encephalomyelitis

Autoimmunity, 2017
Multiple sclerosis (MS) is a highly detrimental autoimmune disease of the central nervous system. There is no cure for it but the treatment typically focuses on subsiding severity and recurrence of the disease.
Weshely Kujur, Rama Krishna Gurram, Sudeep K. Maurya, Sajid Nadeem, Sathi Babu Chodisetti, Nargis Khan, Javed Naim Agrewala   +6 more
doaj   +1 more source

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

sj-doc-1-eae-10.1177_0958305X221084035 - Supplemental material for Removal of hydrochlorothiazide from drinking and environmental water: Hydrolysis, direct and indirect photolysis

, 2022
Supplemental material, sj-doc-1-eae-10.1177_0958305X221084035 for Removal of hydrochlorothiazide from drinking and environmental water: Hydrolysis, direct and indirect photolysis by Maria M.
Branislava Srđenović Čonić (12189614), Maria M. Uzelac (12189611), Sanja J. Armaković (4378033), Nebojša Kladar (12189617), Stevan Armaković (4387363)   +4 more
core   +1 more source

Crystal structure and biochemical analysis of the polyester‐degrading carboxylesterase SM0281 from the symbiotic legume‐associated rhizobacterium Sinorhizobium (Ensifer) meliloti

The FEBS Journal, EarlyView.
The microbial degradation of synthetic polyesters such as polyethylene terephthalate (PET) is mediated by diverse α/β‐hydrolases, many of which remain poorly characterized. In this study, we investigated the α/β‐hydrolase SM0281 from Sinorhizobium meliloti and found that it exhibits robust carboxylesterase and polyesterase activities toward PET, PCL ...
Sofia Lemak, Anna N. Khusnutdinova, Peter J. Stogios, Elena Evdokimova, Alexei Savchenko, Peter N. Golyshin, Elizabeth A. Edwards, Alexander F. Yakunin   +7 more
wiley   +1 more source

Menores creadores de contenidos y publicidad. Aproximación a los derechos y obligaciones para entender y conocer las normas que protegen a los niños frente a la publicidad

Doxa Comunicación, 2023
Ficha técnica: Esther Martínez Pastor e Isabel Serrano Maíllo (Coordinadoras) Editorial Fragua Madrid, 2022 101 pp.
David López Jiménez
doaj   +2 more sources

IDENTIFICACIÓN DE ZONAS CRÍTICAS POR CONTAMINACIÓN ATMOSFÉRICA EN EL ÁREA METROPOLITANA DEL VALLE DE ABURRÁ, para el apoyo en la toma de decisiones de ordenamiento ambiental y territorial

Gestión y Ambiente, 2008
En  este  articulo se presentan los resultados obtenidos para el diagnóstico del recurso Aire en el área  metropolitana  del Valle de Aburrá  hecho por el Grupo de Análisis y Modelamiento Energía Ambiente Economía dentro del  marco del proyecto POMCA ...
CLAUDIA C. RAVE, LUIS A. BUILES, JULIÁN OSSA, RICARDO A. SMITH   +3 more
doaj  

PINK1 and PARKIN Deficiency Increases Neuronal Vulnerability to Autoimmune Neuroinflammation Through Mitochondrial Fragmentation in Aged Mice [PDF]

J Neurochem
PINK1 and Parkin help protect the nervous system during inflammation. When either protein is missing, autoimmune inflammation becomes more severe and neurons show greater mitochondrial abnormalities and damage, particularly with aging. These findings reveal how defective mitochondrial maintenance can make the brain more vulnerable to inflammatory ...
Cossu D, Noda S, Sato S, Yokoyama K, Tomizawa Y, Wang R, Vascellari S, Sechi L, Hatano T, Hattori N.   +9 more
europepmc   +2 more sources

National and International Clinical Guidelines for the Management of Obesity in Adults: A Systematic Review

Obesity Reviews, EarlyView.
ABSTRACT Obesity is a leading risk factor for premature morbidity and mortality, and an increasing public health challenge. This review aimed to systematically identify and appraise national and international clinical guidelines for the management of obesity in adults.
Paul Doody, Ruth Martin, Barrie Tyner, Marie Carrigan, Celine Larkin, Michelle O'Neill, Susan M. Smith, Máirín Ryan   +7 more
wiley   +1 more source

Reseña de: Berrocal Lanzarot, Ana Isabel. Tarjetas y créditos revolving o rotativos: la usura y el control de transparencia

Revista de la Facultad de Derecho, 2021
Reseña de: Berrocal Lanzarot, Ana Isabel. Tarjetas y créditos revolving o rotativos: la usura y el control de transparencia. Madrid: Dykinson, 2020, 348 páginas.
David López Jiménez
doaj