New High-Affinity Monoclonal Antibodies against Shiga Toxin 1 Facilitate the Detection of Hybrid Stx1/Stx2 In Vivo [PDF]
PLoS ONE, 2014 BACKGROUND: Shiga toxin-producing E. coli (STEC) are a group of common and potentially deadly intestinal pathogens expressing Shiga toxin (Stx) as a primary virulence factor.
Stephanie Patfield +2 more
exaly +6 more sources
EBioMedicine, 2015 Background: Syntaxin 1 (STX1) is a presynaptic plasma membrane protein that coordinates synaptic vesicle fusion. STX1 also regulates the function of neurotransmitter transporters, including the dopamine (DA) transporter (DAT).
James S. Sutcliffe +2 more
exaly +4 more sources
The Frequency of Stx1 and Stx2 Genes in Uropathogenic Escherichia coli Isolated From Patients in Kermanshah, Iran [PDF]
Journal of Epigenetics, 2020 1) Background: Uropathogenic E. coli (UPEC) is responsible for 70-90% of urinary tractinfections. On the other hand, E. coli producing Shiga toxin (STEC), the so-called Verotoxinproducing E.
Azadeh Foroughi +1 more
doaj +2 more sources
Recombinant Human Fab Antibodies Differentially Neutralize Shiga Toxin in Renal Epithelial and Endothelial Cells [PDF]
ToxinsHemolytic Uremic Syndrome (HUS) is a severe clinical manifestation primarily triggered by Shiga toxin-producing Escherichia coli (STEC). While Shiga toxins (Stx) are central to the development of systemic endothelial damage, current recombinant antibody ...
Fernando D. Gómez +15 more
doaj +2 more sources
Challenge of multi drug resistant stx1 harboring E. Coli in meat and fast foods [PDF]
Benha Veterinary Medical Journal, 2017 A total of 120 random samples of fresh (30) and processed (90) beef and poultry meat products were collected fromdifferent supermarkets in Menoufia governorates .these samples were examined for the presence of multi –drug resistantStx1 harboring E. Coli,
Mohamed K., Shaimaa N., Amani S.
doaj +2 more sources
Frequency of k99, stx1, and stx2 Virulence Factors in Escherichia coli isolated from Diarrheic and Clinically Healthy Suckling Calves in Sistan and Baluchistan Province, Iran [PDF]
Archives of Razi Institute, 2021 It is necessary to understand the frequency of virulence factor-encoding genes in the assessment of the carriage proportion. Moreover, it is required in the characterization of major unique antigens that are useful in the development of effective ...
N Keykhaei, S Salari, A Rashki
doaj +1 more source
Isolation and identification of Escherichia coli O157:H7 isolated from Veal Meats and Butchers’ Shops in Mosul city, Iraq [PDF]
Journal of Applied Veterinary Sciences, 2022 Escherichia coli (E. coli) O157:H7 is considered a significant food-borne microorganism that causes food poisoning infections in humans every year. E. coli O157:H7 has various virulence factors such as Shiga-toxin encoding (Stx1 and Stx2).
Shaker Othman +2 more
doaj +1 more source
Incidence and molecular characterization of Escherichia coli in some dairy products [PDF]
Benha Veterinary Medical Journal, 2019 Escherichia coli is one of the foodborne pathogens associated with several cases of human sickness. The present study was undertaken to estimate the incidence of E. coli, in total of one hundred and twenty random samples of some dairy products ; Raw milk,
Ekbal M.A. Ibrahim +3 more
doaj +1 more source
شناسایی اشریشیا کلی تولید کننده شیگاتوکسین (STEC) در مدفوع گوساله های به ظاهر سالم در شهرستان مشهد، ایران [PDF]
Archives of Razi Institute, 2015 هدف از مطالعه حاضر شناسایی سویه های حدت دار STEC جداشده از مدفوع 100 گوساله به ظاهر سالم می باشد. در مطالعه حاضر، 100 جدایه اشریشیا کلی از مدفوع گوساله های به ظاهر سالم متعلق به شش گله مختلف در استان خراسان رضوی از جهت حضور ژن های حدت مشخصه سویه های STEC
عبدالله جمشیدی +2 more
doaj +1 more source
Characterization of verotoxigenic E.coli and enteropathogenic E.coli isolated from infants with diarrhea in combination with antimicrobial resistance pattern in Minia, Egypt [PDF]
Journal of Advanced Biomedical and Pharmaceutical Sciences, 2020 Diarrheal disease is considered a significant health problem, principally in developing countries as it is one of the leading causes of morbidity and mortality especially in infants. Studies found that STES and EPEC strains are among the most predominant
Shimaa Abd El Gany +3 more
doaj +1 more source