Intranasal delivery of shRNA to knockdown the 5HT-2A receptor enhances memory and alleviates anxiety
Short-hairpin RNAs (shRNA), targeting knockdown of specific genes, hold enormous promise for precision-based therapeutics to treat numerous neurodegenerative disorders.
Troy T. Rohn +7 more
doaj +1 more source
Numbers and distribution of eagles in the Czech Republic: reason for optimism
At present, four eagle species are regular breeders in the Czech Republic: White Tailed Sea-Eagle (Haliaeetus albicilla), Eastern Imperial Eagle (Aquila heliaca), Lesser Spotted Eagle (Aquila [Clanga] pomarina), and Golden Eagle (Aquila chrysaetos ...
Tomáš Bělka, David Horal
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The prey of the Harpy Eagle in its last reproductive refuges in the Atlantic Forest
The Harpy Eagle (Harpia harpyja) is threatened with extinction throughout its distribution in the neotropical forests. In the Atlantic Forest, deforestation has reduced the number of suitable habitats, with only a few remnant forest fragments hosting ...
Mylena Kaizer +5 more
doaj +1 more source
Glacial Processes and Their Relationship to Streamflow Flute Glacier, Alaska [PDF]
Flute Glacier is located at the head of the South Fork of Eagle River, Alaska, about twenty air-miles east northeast of Anchorage. It is a small north-facing glacier, approximately two miles long and half a mile wide, situated in a deep glacial ...
Long, William E.
core
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Birds of Malagos Watershed: A Comparative Sourvey
The study titled "Birds of Malagos Watershed, Southeastern Philippines" highlights the avifaunal richness of Mindanao, one of the most biodiverse islands in the Philippines.
Geonsyl L. Alviola +3 more
doaj +1 more source
The effects of childbirth-related post-traumatic stress disorder on women and their relationships: a qualitative study [PDF]
There is converging evidence that 1%-2% of women develop post-traumatic stress disorder (PTSD) as a result of childbirth. The current study aimed to explore the long-term effects of childbirth-related PTSD on women, their relationship with their partner ...
Ayers, Susan, Eagle, A, Waring, H
core +2 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Use of bioelectrical impedance spectroscopy to provide a measure of body composition in sows
The ability to accurately estimate fat mass and fat-free mass (FFM) has the potential to improve the way in which sow body condition can be managed in a breeding herd. Bioelectrical impedance spectroscopy (BIS) has been evaluated as a practical technique
T.L. Muller +6 more
doaj +1 more source

