Results 61 to 70 of about 653,076 (299)

EAGLE—A Scalable Query Processing Engine for Linked Sensor Data [PDF]

open access: yes, 2019
Recently, many approaches have been proposed to manage sensor data using semantic web technologies for effective heterogeneous data integration. However, our empirical observations revealed that these solutions primarily focused on semantic relationships
G. Breslin, John   +4 more
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Necessary condition of diamond like carbon coated mechanical seals for nitrogen gas

open access: yesNihon Kikai Gakkai ronbunshu, 2017
Necessary conditions for usage of DLC coated mechanical seals were investigated by using ring on ring type sliding tests under various contact pressures and sliding speeds in dry and wet nitrogen.
Masao OKA, Norio UEMURA, Koshi ADACHI
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Identification of sex-specific SNPS in burbot Lota lota using RAD sequencing: conservation and management applications

open access: yesFisheries and Aquatic Sciences, 2019
The development of sex-specific genetic assays in a species provides both a method for identifying the system of sex determination and a valuable tool to address questions of conservation and management importance.
Ninh V. Vu   +3 more
doaj   +1 more source

Mating systems and predictors of relative reproductive success in a Cutthroat Trout subspecies of conservation concern

open access: yesEcology and Evolution, 2021
Mating systems and patterns of reproductive success in fishes play an important role in ecology and evolution. While information on the reproductive ecology of many anadromous salmonids (Oncorhynchus spp.) is well detailed, there is less information for ...
John S. Hargrove   +4 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

First lactation performance of sows in Maternity Ring housing is comparable to that in farrowing crates

open access: yesFrontiers in Veterinary Science
There is a trade-off between sow and piglet welfare in farrowing pens, whereby increased behavioural freedom of sows results in unacceptable levels of piglet mortality.
Kate J. Plush   +4 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Conservation Status of Breeding Eagles in France

open access: yesПернатые хищники и их охрана, 2019
Seven species of eagle breed in France: Golden Eagle (Aquila chrysaetos), Lesser Spotted Eagle (Aquila pomarina), Bonelli’s Eagle (Aquila fasciata), Booted Eagle (Hieraaetus pennatus), Short-toed Eagle (Circaetus gallicus), Osprey (Pandion haliaetus) and
Hugo Pontalier   +7 more
doaj   +1 more source

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