Results 91 to 100 of about 171,863 (295)

The role of laboratories in mitigating the threat of Security Sensitive Biological Agents to animal health and agriculture [PDF]

open access: yesMicrobiology Australia, 2020
The aim of Australia’s Security Sensitive Biological Agents (SSBAs) Regulatory Scheme is to limit opportunities for acts of bioterrorism or criminal acts using harmful biological agents.
Debbie Eagles
doaj  

A Support Tool for Tagset Mapping

open access: yes, 1995
Many different tagsets are used in existing corpora; these tagsets vary according to the objectives of specific projects (which may be as far apart as robust parsing vs. spelling correction).
Teufel, Simone
core   +2 more sources

Modelling Discourse-related terminology in OntoLingAnnot’s ontologies [PDF]

open access: yes, 2010
Recently, computational linguists have shown great interest in discourse annotation in an attempt to capture the internal relations in texts. With this aim, we have formalized the linguistic knowledge associated to discourse into different linguistic ...
Aguado de Cea, G., Pareja-Lora, A.
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

The Cowl - v.82 - n.16 - Feb 8, 2018 [PDF]

open access: yes, 2018
The Cowl - student newspaper of Providence College. Volume 82, Number 16 - February 8, 2018.

core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Growth response to temperature of two maize (Zea mays L.) hybrids with differing levels of cold tolerance : a thesis presented in partial fulfillment of the requirements for the degree of Master of Agricultural Science in Plant Science (Seed Technology), Massey University [PDF]

open access: yes, 1993
Low temperatures are a hazard to maize production especially in high altitude and high latitude areas (Eagles, 1979; Hardacre and Eagles, 1986) where it may cause substantial yield reductions through its accumulated effect on vegetative and reprodutive ...
Mukumbuta, Mwangala Stephen
core  

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Spatial patterns in the evolution of Cenozoic dynamic topography and its influence on the Antarctic continent [PDF]

open access: yes, 2013
Our knowledge of dynamic topography in Antarctica remains in an infancy stage compared to other continents. We assess the space-time variability in dynamic topography in Antarctica by analysing grids of global dynamic topography in the Cenozoic (and late
Anderson, L.   +4 more
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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