Results 71 to 80 of about 34,741 (308)
Wildlife Society Bulletin, 2016 Lead (Pb) exposure in free‐flying bald eagles (Haliaeetus leucocephalus) is an important conservation concern. One of the challenges to characterizing the magnitude of Pb exposure in free‐flying bald eagles is obtaining samples.
William J. Reiter‐Marolf +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
fMRI Repetition Suppression During Generalized Social Categorization
Scientific Reports, 2017 Correctly identifying friends and foes is integral to successful group living. Here, we use repetition suppression to examine the neural circuitry underlying generalized group categorization—the process of categorizing in-group and out-group members ...
Tatiana Lau, Mina Cikara
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Vogeldarstellungen auf karolingischen Flechtwerksteinen in Karantanien
Arheološki Vestnik, 2018 /
Paul Gleirscher, Brigitte Ponta-Zitterer
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
The role of laboratories in mitigating the threat of Security Sensitive Biological Agents to animal health and agriculture [PDF]
Microbiology Australia, 2020 The aim of Australia’s Security Sensitive Biological Agents (SSBAs) Regulatory Scheme is to limit opportunities for acts of bioterrorism or criminal acts using harmful biological agents.
Debbie Eagles
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