Results 81 to 90 of about 171,863 (295)
Goblins, Greed, and Goodness: The Symbolic and Narrative Degradation of Goblins within The Hobbit [PDF]
Throughout The Hobbit, J.R.R Tolkien establishes a variety of races that range on a diverse scale of good and evil. Within this spectrum, Goblins are portrayed as being the most evil in comparison to every other race on Middle Earth. Tolkien utilizes a
Stine, Katelyn
core +1 more source
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Vogeldarstellungen auf karolingischen Flechtwerksteinen in Karantanien
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Paul Gleirscher, Brigitte Ponta-Zitterer
doaj
fMRI Repetition Suppression During Generalized Social Categorization
Correctly identifying friends and foes is integral to successful group living. Here, we use repetition suppression to examine the neural circuitry underlying generalized group categorization—the process of categorizing in-group and out-group members ...
Tatiana Lau, Mina Cikara
doaj +1 more source
Audit report on the City of Mount Union, Iowa for the year ended June 30, 2006 [PDF]
Audit report on the City of Mount Union, Iowa for the year ended June 30 ...
core
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi +6 more
wiley +1 more source
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source

