Results 121 to 130 of about 441,758 (309)
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei+15 more
wiley +1 more source
Otic Neurogenesis Is Regulated by TGFβ in a Senescence-Independent Manner
Cellular senescence has classically been associated with aging. Intriguingly, recent studies have also unraveled key roles for senescence in embryonic development, regeneration, and reprogramming.
Marta Magariños+9 more
doaj +1 more source
Accurate Detection of Inner Ears in Head CTs Using a Deep Volume-to-Volume Regression Network with False Positive Suppression and a Shape-Based Constraint [PDF]
Cochlear implants (CIs) are neural prosthetics which are used to treat patients with hearing loss. CIs use an array of electrodes which are surgically inserted into the cochlea to stimulate the auditory nerve endings. After surgery, CIs need to be programmed.
arxiv
Inner ear disturbances related to middle ear inflammation [PDF]
2017-02The inner and middle ear are connected mainly through round and oval windows, and inflammation in the middle ear cavity can spread into the inner ear, which might induce a disturbance.
69453, Sone, Michihiko
core
Endogenous bone marrow stem cell mobilization in rats: Its potential role in homing and repair of damaged inner ear [PDF]
The stem cells are widely used in the last few years in different fields of medicine, either by external transplantation or endogenous mobilization, most of these studies are still experimental on animals; few were tried on humans as in the spinal cord ...
Abdel-Salam, Seddik+4 more
core +2 more sources
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng+11 more
wiley +1 more source
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley +1 more source
Neuroimaging for differential diagnosis of transient neurological attacks
Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley +1 more source
Hand bone conduction sound study by using the DSP Logger MX 300 [PDF]
Bone conduction is the transmission of acoustic energy to the inner ear by different paths involving the bones of the skull. In this work, we use the path the hand provides in order to transmit the sound coming from the cell phone using Bluetooth system.
arxiv
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du+13 more
wiley +1 more source