Results 231 to 240 of about 434,910 (305)

Principles of gene therapy of the inner ear. [PDF]

Curr Opin Otolaryngol Head Neck Surg
Lin JS, Shibata SB.
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

The effects of mitochondrial damage and energy metabolism disorders on the progression of noise-induced deafness and its treatment. [PDF]

Head Face Med
Xu L, Jiang H.
europepmc   +1 more source

Fast Small‐Angle X‐Ray Scattering Tensor Tomography: An Outlook into Future Applications in Life Sciences

Small Methods, EarlyView.
This study reveals the future potential of SAXS tensor tomography at macromolecular X‐ray crystallography beamlines and life sciences applications. A new standard in fast data acquisition is set, allowing for up‐to 10x higher throughput. The measurements show mineralised collagen fibrils within the incus bone of the human auditory ossicle.
Christian Appel, Margaux Schmeltz, Irene Rodriguez‐Fernandez, Lukas Anschuetz, Leonard C. Nielsen, Ezequiel Panepucci, Tomislav Marijolovic, Klaus Wakonig, Aleksandra Ivanovic, Anne Bonnin, Filip Leonarski, Justyna Wojdyla, Takashi Tomizaki, Manuel Guizar‐Sicairos, Kate Smith, John H. Beale, Wayne Glettig, Katherine E. McAuley, Oliver Bunk, Meitian Wang, Marianne Liebi   +20 more
wiley   +1 more source

Protocol for vibratome sectioning, immunofluorescence, and S-phase labeling of inner ear organoids. [PDF]

STAR Protoc
Wu J, Heller S, Matern MS.
europepmc   +1 more source

The effects of artificial intelligence on organizational culture in the perspective of the hermeneutic cycle: The intersection of mental processes

Systems Research and Behavioral Science, EarlyView.
Abstract Artificial intelligence technology has spread rapidly in the business world in recent years and has transformed the business processes of many organizations. This transformation has caused significant changes not only in the technological infrastructure but also in the organizational culture and way of doing business.
Aslıhan Canbul Yaroğlu
wiley   +1 more source

Motion blur aware multiscale adaptive cascade framework for ear tag dropout detection in reserve breeding pigs. [PDF]

Sci Rep
Duan W, Wang F, Fu X, Li H, Wang B.
europepmc   +1 more source

Cup Deep Drawing Simulation of Commercially Pure Titanium for Varying‐Shoulder‐Radius Die Using Finite Element Method and Non‐associated Flow Rule

steel research international, EarlyView.
Finite element simulations of deep drawing of commercially pure titanium sheets using single‐radius and varying‐shoulder‐radius dies are conducted. Two types of nonassociated flow rules are applied, and the results are verified by comparing them with the experimental results.
Yuji Sato, Shogo Nishioka, Yutaro Akiguchi, Honghao Wang, Jun Yanagimoto   +4 more
wiley   +1 more source