Results 101 to 110 of about 3,155,969 (318)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Addressing Migration Stigma in Latin America Using Mental Health Registry-Based Data

International Journal of Public Health
BackgroundLatin America is experiencing unprecedented migration, with millions, including many political refugees, moving within and across the region.
Franco Mascayano, Franco Mascayano, Emily Dunkel, Param Sampat, Katrina M. Rodriguez, Rodrigo Casanueva, Jeanette A. Stingone, Ezra Susser, Lawrence H. Yang, Lawrence H. Yang   +9 more
doaj   +1 more source

The Spanish Banks' Strategy in Latin America [PDF]

The expansion of Spanish banks in Latin America is one of the most important elements of bank internationalisation in recent years. At first glance, it is paradoxical that at a time of notable progress in the process of European integration, there is an ...
Carmen Hernansanz, Miguel Sebasti‡n, Morten Balling   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

S216: CLINICAL ACTIVITY OF CC-99282, A CEREBLON E3 LIGASE MODULATOR (CELMOD) AGENT, IN PATIENTS (PTS) WITH RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA (R/R NHL) – RESULTS FROM A PHASE 1, OPEN-LABEL STUDY

HemaSphere, 2022
J.-M. Michot, J. C. Chavez, C Carpio, S. Ferrari, T. A. Feldman, D. Morillo, J. Kuruvilla, A. Pinto, V. Ribrag, E Bachy, T. J. Buchholz, S. Carrancio, W.-C. Chou, C. Guarinos, F. Wu, S. Li, P. Patah, M. Pourdehnad, L. Nastoupil   +18 more
doaj   +1 more source

Growth and Income Poverty in Latin America and the Caribbean: Evidence from Household Surveys [PDF]

This paper provides evidence on growth and income poverty in Latin American and the Caribbean. Results are obtained by processing microdata from household surveys of 18 LAC countries covering the 1990s and early 2000s.
Federico Gutiérrez, Leonardo Gasparini, Leopoldo Tornarolli   +2 more
core  

Developing Community Connections: Qualitative Research Regarding Framing Policies [PDF]

, 2003
The objective of this phase of research was to determine how Prevent Child Abuse America can effectively frame the organization's communications to advance a broad agenda of policies for children and families, including both policies that directly ...
Meg Bostrom
core  

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Early Human Development - Equity from the Start - Latin America

Revista Latinoamericana en Ciencias Sociales, Niñez y Juventud, 2009
En la actualidad sabemos, a partir de estudios en ciencias sociales y en neurobiología del desarrollo, que el medio ambiente en los primeros años del desarrollo humano determina el comportamiento de la salud (física y mental), el aprendizaje y el ...
J Fraser Mustard
doaj