Results 81 to 90 of about 6,948,353 (298)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Radio program summarizing segments aired by Voice of America in 1988
برنامج إذاعي يلخص المقاطع التي غطتها إذاعة صوت أمريكا عام 1988، منها تقارير عن إستمرار الإنتفاضة الفلسطينية، عودة العلاقات المصرية العربية، نهاية الحرب بين العراق وإيران.
Voice of America, Egypt
core +2 more sources
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
1981 Miss Wheelchair America Pageant program
Front cover of the Miss Wheelchair America Pageant 1980 program, including the MWA logo printed in the center and the words "Ninth Annual Pageant 1981" printed ...
Miss Wheelchair America Pageant.
core
Review of "Speaking with the Dead in Early America" by William J. Scheick.
Erik R. Seeman. Speaking with the Dead in Early America. Philadelphia: University of Pennsylvania Press, 2019. ix + 329 pp. + 25 illus. $39.95. Review by William J.
Scheick, William J.
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Early Orndorff Papers, 1868-1942
Papers, 1868-1942, of the King and Orndorff families of Van Buren Furnace, Shenandoah County, Va. The collection includes papers, 1891-1942, of Early Orndorff, documents in German of a maternal ancestor, Emily Wilde, who came to America in 1877 and ...
Rochling, G.H., Orndorff, Early
core
1980 Miss Wheelchair America Pageant program
Front cover of the Miss Wheelchair America Pageant 1980 program, including the MWA logo printed in the center and "Eighth Annual Pageant 1980" printed ...
Miss Wheelchair America Pageant.
core
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

