Results 101 to 110 of about 2,391,716 (307)

Early Tumor Shrinkage and Depth of Response as Predictive Markers of Treatment Response and Prognosis in Solid Tumors

Cancer Medicine
Background Evaluation of tumor efficacy is central to cancer care. Progression‐free survival (PFS) is widely used as an early surrogate for treatment effectiveness, but more timely and reliable biomarkers are needed. Early tumor shrinkage (ETS) and depth
Peng Cao, Xiaojuan Yang
doaj   +1 more source

Levosimendan in Sepsis. [PDF]

, 2017
Commentum to "Levosimendan for the Prevention of Acute Organ Dysfunction in ...
Morelli, Andrea, Tritapepe, Luigi
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Clues About Bluffing in Clue: Is Conventional Wisdom Wise?

, 2019
We have used the board game Clue as a pedagogical tool in our course on Artificial Intelligence to teach formal logic through the development of logic-based computational game-playing agents.
Hansen, David, Hansen, Kyle D.
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

External validation of a serum tumor marker algorithm for early prediction of no durable benefit to immunotherapy in metastastic non-small cell lung carcinoma

Tumor Biology
Background Immune checkpoint inhibitors (ICIs) provide a significant survival benefit in non-small cell lung cancer (NSCLC) patients; however, accurately predicting which patients will benefit remains a challenge.
Milou M. F. Schuurbiers, Freek A. van Delft, Hendrik Koffijberg, Maarten J. IJzerman, Kim Monkhorst, Marjolijn J. L. Ligtenberg, Daan van den Broek, Huub H. van Rossum, Michel M. van den Heuvel   +8 more
doaj   +1 more source

Application and progress of nomograms in gastric cancer

Frontiers in Medicine
Gastric cancer, as one of the malignant tumors with a significant disease burden globally, emphasizes the importance of early diagnosis and personalized treatment for improving patient prognosis.
Haiyu Wang, Yumin Ding, Min Zhuang, Kaixu Li, Shujing Zhao, Dehong Li   +5 more
doaj   +1 more source

Poverty, education, and health in Indonesia : who benefits from public spending? [PDF]

The authors investigate the extent to which Indonesia's poor benefit from public and private provisioning of education and health services. Drawing on multiple rounds of SUSENAS household surveys, they document a reversal in the rate of decline in ...
Lanjouw, Peter, Pradhan, Menno, Saadah, Fadia, Sayed, Haneen, Sparrow, Robert   +4 more
core  

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Using Achievement Tests to Measure Language Assimilation and Language Bias among Immigrant Children [PDF]

We use Woodcock Johnson III child assessment data in the New Immigrant Survey to examine language assimilation and test score bias among children of Hispanic immigrants.
Akresh, Richard, Redstone Akresh, Ilana
core