Results 111 to 120 of about 2,391,716 (307)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The Impact on Women of the Coalition Spending Review 2010 [PDF]

open access: yes, 2010
This report provides a gender impact assessment of the Coalition Government's 2010 Spending ...
Annesley, Claire, Himmelweit, Susan
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

La stima del valore di opzione e del valore di esistenza delle risorse naturali: il caso del «Pinus leucodermis» del Pollino

open access: yesAestimum, 2009
The economic evaluation of ecosystem services dates back as early as the fifties. Only recently, however, the assessment of non-use values has received duly attention in benefit-cost analysis. In this paper, after a review of the current state of the art
Severino Romano
doaj   +1 more source

Synergistic combination of systems for structural health monitoring and earthquake early warning for structural health prognosis and diagnosis [PDF]

open access: yes, 2012
Earthquake early warning (EEW) systems are currently operating nationwide in Japan and are in beta-testing in California. Such a system detects an earthquake initiation using online signals from a seismic sensor network and broadcasts a warning of the ...
Beck, James L., Wu, Stephen
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Practice development plans to improve the primary care management of acute asthma: randomised controlled trial

open access: yesBMC Family Practice, 2007
Background Our professional development plan aimed to improve the primary care management of acute asthma, which is known to be suboptimal. Methods We invited 59 general practices in Grampian, Scotland to participate. Consenting practices were randomised
Price David   +5 more
doaj   +1 more source

Kazakhstan's Pension System: Pressures for Change and Dramatic Reforms [PDF]

open access: yes
Five years ago, Kazakhstan embarked on a dramatic reform of its pension and social security system in order to move from an unsustainable public defined benefit ("solidarity") system to one of defined mandatory contributions (accumulative system).
Becker, Charles M., Seitenova, Ai-Gul S.
core  

Health Insurance Exchanges: How Economic and Financial Modeling Can Support State Implementation [PDF]

open access: yes, 2010
Outlines considerations for modeling the impact of state health insurance exchanges on states, including size and number of exchanges; demographics, health status, and health costs of the newly covered; and extent of collaboration with other ...
Julie Sonier, Patrick Holland
core  

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