Results 11 to 20 of about 2,391,716 (307)

Deep Brain Stimulation in Early-Stage Parkinson’s Disease: Patient Experience after 11 Years

Brain Sciences, 2022
The deep brain stimulation (DBS) in early-stage Parkinson’s disease (PD) pilot trial began more than a decade ago and remains the only investigation of DBS in mildly symptomatic patients.
Kaitlyn Stoehr, Kian Pazira, Kemberlee Bonnet, David Schlundt, David Charles, Mallory Hacker   +5 more
doaj   +1 more source

A benefit-cost analysis framework for prioritization of control programs for well-established invasive alien species [PDF]

NeoBiota, 2021
Invasive alien species (IAS) are identified as a major threat to biodiversity and ecosystem services. While early detection and control programs to avoid establishments of new alien species can be very cost-effective, control costs for well-established ...
Rakel Blaalid, Kristin Magnussen, Nina Bruvik Westberg, Ståle Navrud   +3 more
doaj   +3 more sources

A production-cost-simulation-based method for optimal planning of the grid interconnection between countries with rich hydro energy

Global Energy Interconnection, 2020
Cross-border grid interconnection is a critical means to achieve wide-area share of hydro and other clean energy. Economic benefit assessment of cross-border grid interconnection projects should be carefully performed during early stage. In this paper, a
Caihao Liang, Jing Meng, Chen Chen, Yuanbing Zhou   +3 more
doaj   +1 more source

Clinical relevance of sentinel lymph node biopsy in early ovarian cancer [PDF]

Obstetrics & Gynecology Science, 2023
The first-line treatment for early ovarian cancer typically involves primary debulking surgery aimed at maximal cytoreduction, alongside adjuvant chemotherapy if clinically indicated.
Ki Eun Seon, Sang Wun Kim, Young Tae Kim
doaj   +1 more source

Assessing the Clinical Benefit of Systemic Adjuvant Therapies for Early Breast Cancer [PDF]

Geburtshilfe und Frauenheilkunde, 2017
AbstractOncologic therapy is currently undergoing significant changes. A number of innovative targeted medications currently in clinical development have raised high expectations. With that in mind, discussions about terms such as “clinical benefit” and “clinical relevance” are highly topical.
Möbus, Volker, Hell, Susanne, Schmidt, Marcus   +2 more
openaire   +3 more sources

Benefits of economic assessment of cyclone early warning systems - A case study on Cyclone Evan in Samoa

Progress in Disaster Science, 2019
Samoa is extremely exposed to natural hazards, particularly tropical cyclones and earthquake-generated tsunami. Some studies have put forth the position that adequate investment in early warning systems can contribute to the social and economic well ...
Bapon S.H.M. Fakhruddin, Lauren Schick
doaj   +1 more source

“Market withdrawals” of medicines in Germany after AMNOG: a comparison of HTA ratings and clinical guideline recommendations

Health Economics Review, 2018
Background According to the AMNOG act, the German Federal Joint Committee (G-BA) determines the additional benefit of new medicines as a basis for subsequent price negotiations.
Thomas R. Staab, Miriam Walter, Sonja Mariotti Nesurini, Charalabos-Markos Dintsios, J.-Matthias Graf von der Schulenburg, Volker E. Amelung, Jörg Ruof   +6 more
doaj   +1 more source

Inconsistent approaches of the G-BA regarding acceptance of primary study endpoints as being relevant to patients - an analysis of three disease areas: oncological, metabolic, and infectious diseases

BMC Health Services Research, 2016
Background Previous evaluations of oncological medicines in the German early benefit assessment (EBA) procedure have demonstrated inconsistent acceptance of endpoints by regulatory authorities and the Federal Joint Committee (G-BA).
Thomas Staab, Georg Isbary, Volker E. Amelung, Jörg Ruof   +3 more
doaj   +1 more source

Commentary: Early screening parameters for dysphagia in acute ischemic stroke [PDF]

, 2018
We read with great interest the article by Henke et al. (1) aimed to identify early assessable predictors of dysphagia in the acute phase of ischemic stroke.
Piero, Vittorio Di, Toscano, Massimiliano, Viganò, Alessandro   +2 more
core   +2 more sources

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source