Results 21 to 30 of about 2,405,285 (205)

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source

Cardiac evaluation of young athletes: Time for a risk-based approach? [PDF]

, 2020
Pre-participation cardiovascular screening (PPCS) is recommended by several scientific and sporting organizations on the premise that early detection of cardiac disease provides a platform for individualized risk assessment and management; which has been
Drezner, JA, MacLachlan, H
core   +1 more source

Different interpretation of additional evidence for HTA by the commissioned HTA body and the commissioning decision maker in Germany: whenever IQWiG and Federal Joint Committee disagree

Health Economics Review, 2019
Background The purpose of this study was to analyse the impact of commissioned addenda by the Federal Joint Committee (FJC) to the HTA body (IQWiG) and their agreement with FJC decisions and to identify potential additional decisive factors of FJC ...
C. M. Dintsios, F. Worm, J. Ruof, M. Herpers   +3 more
doaj   +1 more source

Qualitative assessment of innovations in healthcare provision

BMC Health Services Research, 2009
Background The triad of quality, innovation and economic restraint is as important in health care as it is in the business world. There are many proposals for the assessment of quality and of economic restraints in health care but only a few address ...
Ghosh Amit K, Porzsolt Franz, Kaplan Robert M   +2 more
doaj   +1 more source

Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper

Journal of Translational Medicine, 2023
Background In drug development, few molecules from a large pool of early candidates become successful medicines after demonstrating a favourable benefit-risk ratio.
Chao Chen, Xuan Zhou, Silvia Maria Lavezzi, Usman Arshad, Raman Sharma   +4 more
doaj   +1 more source

Quantitative Benefit–Risk Assessment of COVID-19 Vaccines Using the Multi-Criteria Decision Analysis

Vaccines, 2022
In the early SARS-CoV-2 (COVID-19) pandemic, four major vaccines were approved despite limited efficacy and safety data through short regulatory review periods. Thus, it is necessary to assess the benefit-risk (BR) profiles of the COVID-19 vaccines.
Kyung-Hwa Son, Sun-Hong Kwon, Hye-Jung Na, Youngsuk Baek, Inok Kim, Eui-Kyung Lee   +5 more
doaj   +1 more source

Association between patient outcomes and key performance indicators of stroke care quality: A systematic review and meta-analysis [PDF]

, 2017
Purpose: Translating research evidence into clinical practice often uses key performance indicators to monitor quality of care. We conducted a systematic review to identify the stroke key performance indicators used in large registries, and to estimate
Cadilhac, Dominique A., Kagwiza, Jeanne N., Langhorne, Peter, Urimubenshi, Gerard, Wu, Olivia   +4 more
core   +1 more source

States of Uncertainty, Risk–Benefit Assessment and Early Clinical Research: A Conceptual Investigation

Science and Engineering Ethics, 2022
AbstractIt can be argued that there is an ethical requirement to classify correctly what is known and what is unknown in decision situations, especially in the context of biomedicine when risks and benefits have to be assessed. This is because other methods for assessing potential harms and benefits, decision logics and/or ethical principles may apply ...
Antje Schnarr, Marcel Mertz
openaire   +2 more sources

The impact of early comprehensive geriatric screening on the readmission rate in an acute geriatric ward: a quasi-experimental study

BMC Geriatrics, 2019
Background Unplanned readmission is an important healthcare quality issue. We studied the effect of a comprehensive geriatric screen (CGS) in the early admission course followed by a comprehensive geriatric assessment on readmission rates in elderly ...
Kun-Pei Lin, Jen-Hau Chen, Feng-Ping Lu, Chiung-Jung Wen, Ding-Cheng (Derrick) Chan   +4 more
doaj   +1 more source

Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis [PDF]

, 2011
Introduction Improved nutrition is the major proven benefit of newborn screening programmes for cystic fibrosis (CF) and is associated with better clinical outcomes.
Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF), Brennan, Siobhan, Gangell, Catherine, Parsons, Faith, Ranganathan, Sarath C, Sly, Peter D, Stick, Stephen M   +6 more
core   +1 more source