Results 41 to 50 of about 2,405,285 (205)

Impact of the Early Benefit Assessment on A Pharmaceutical's Real Consumption in Germany [PDF]

Value in Health, 2014
The Act on the Reform of the Market for Medicinal Products (“AMNOG”) introduced an early benefit assessment (EBA) of pharmaceuticals in Germany in 2011. According to this law, all pharmaceuticals with a new active agent made available on the market for the first time have to go through a benefit assessment process.
Kotowa, W., Häussler, B., Reindl, S., Höer, A.   +3 more
openaire   +2 more sources

Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. [PDF]

, 2018
BACKGROUND: Acute asthma attack is a frequent condition in children. It is one of the most common reasons for emergency department (ED) visit and hospitalization. Appropriate care is fundamental, considering both the high prevalence of asthma in children,
Chiappini, E, Corsello, G, Indinnimeo, L, Miraglia del Giudice, M   +3 more
core   +1 more source

An economic benefit evaluation model and its application for optimizing transmission capacity of multinational interconnections

CSEE Journal of Power and Energy Systems, 2018
Multinational power grid interconnections play a critical part in supporting the vision of global energy internet. During the early stages of the Global Energy Internet, the value proposition of multinational interconnections should be carefully ...
Xiaojun Wang, Ruimin Jiang, Pei Zhang, Yunfei Mu, Maosheng Ding   +4 more
doaj   +1 more source

Establishing cost-effectiveness of genetic targeting of cancer therapies [PDF]

, 2011
The clinical benefit of a new genomic instrument, the 70-gene signature for breast cancer patients, is being evaluated in a randomised clinical trial. The early, controlled implementation process is supported by a Constructive Technology Assessment to ...
Harten, W.H. van, Joore, M.A., Retèl, Valesca P., Rutgers, E.J.Th.   +3 more
core   +1 more source

Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]

, 2016
Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core   +2 more sources

Conceptual Framework to Guide Early Diagnosis Programs for Symptomatic Cancer as Part of Global Cancer Control

JCO Global Oncology, 2021
Diagnosing cancer earlier can enable timely treatment and optimize outcomes. Worldwide, national cancer control plans increasingly encompass early diagnosis programs for symptomatic patients, commonly comprising awareness campaigns to encourage prompt ...
Minjoung Monica Koo, Karla Unger-Saldaña, Amos D. Mwaka, Marilys Corbex, Ophira Ginsburg, Fiona M. Walter, Natalia Calanzani, Jennifer Moodley, Greg P. Rubin, Georgios Lyratzopoulos   +9 more
doaj   +1 more source

Establishing cost-effectiveness of genetic targeting of cancer therapies\ud [PDF]

, 2008
The clinical benefit of a new genomic instrument, the 70-gene signature\ud for breast cancer patients, is being evaluated in a randomised clinical\ud trial.
Harten, W.H. van, Joore, M.A., Retèl, Valesca P., Rutgers, E.J.Th.   +3 more
core   +2 more sources

Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients. [PDF]

, 2018
In December 2017, the National Academy of Neuropsychology convened an interorganizational Summit on Population Health Solutions for Assessing Cognitive Impairment in Geriatric Patients in Denver, Colorado. The Summit brought together representatives of a
Adler, Deb, Alban, Christopher, Bondi, Mark, Braun, Michelle, Cagigas, Xavier, Daven, Morgan, Denney, Robert L, Drozdick, Lisa, Foster, Norman L, Golden, Tamara, Hwang, Ula, Iverson, Grant, Ivey, Laurie, Kramer, Joel, Lacritz, Laura, Lantz, Melinda, Latts, Lisa, Ling, Shari M, Malone, Michael, Maria Lopez, Ana, Martin-Plank, Lori, Maslow, Katie, McConnel, Charles E, Melady, Don, Messer, Melissa, Meyers, John, Most, Randi, Norris, Margaret P, Perry, William, Pliskin, Neil, Roebuck-Spencer, Tresa, Shafer, David, Silver, Cheryl, Silverberg, Nina, Thomas, Colin M, Thornhill, Laura, Tsai, Jean, Vakharia, Nirav, Waters, Martin   +38 more
core   +2 more sources

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup. [PDF]

, 2017
Purpose: Current clinical parameters do not stratify indolent from aggressive prostate cancer. Aggressive prostate cancer, defined by the progression from localized disease to metastasis, is responsible for the majority of prostate cancer–associated ...
Alshalalfa, Mohammed,, Bowden, Michaela,, Brown, Myles,, Davicioni, Elai,, Den, Robert B.,, Ellis, Leigh,, Eng, Kevin H.,, Erho, Nicholas,, Feng, Felix Y.,, Galbo, Phillip,, Goodrich, David W.,, Gray, Kathryn P.,, Huang, Ying,, Jenkins, Robert B.,, Karnes, R. Jeffrey,, Ku, Sheng Yu,, Labbé, David P.,, Lund University., Rosario, Spencer,, Ross, Ashley E., Schaeffer, Edward M.,, Sjöström, Martin,, Spratt, Daniel E.,, Sweeney, Christopher J.,, Wadosky, Kristine M.,   +24 more
core   +2 more sources

Treatment algorithm for infants diagnosed with spinal muscular atrophy through newborn screening [PDF]

, 2018
Spinal muscular atrophy (SMA) is an autosomal recessive disease characterized by the degeneration of alpha motor neurons in the spinal cord, leading to muscular atrophy.
Connolly, Anne, Crawford, Thomas O, Darras, Basil, Day, John, Finkel, Richard, Glascock, Jacqueline, Haidet-Phillips, Amanda, Howell, R. Rodney, Jarecki, Jill, Ker, Douglas, Klinger, Katherine, Kuntz, Nancy, Prior, Thomas, Sampson, Jacinda, Shieh, Perry B   +14 more
core   +2 more sources