Results 51 to 60 of about 2,391,716 (307)

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

AI-enabled routine H&E image based prognostic marker for early-stage luminal breast cancer

npj Precision Oncology, 2023
Breast cancer (BC) grade is a well-established subjective prognostic indicator of tumour aggressiveness. Tumour heterogeneity and subjective assessment result in high degree of variability among observers in BC grading.
Noorul Wahab, Michael Toss, Islam M. Miligy, Mostafa Jahanifar, Nehal M. Atallah, Wenqi Lu, Simon Graham, Mohsin Bilal, Abhir Bhalerao, Ayat G. Lashen, Shorouk Makhlouf, Asmaa Y. Ibrahim, David Snead, Fayyaz Minhas, Shan E. Ahmed Raza, Emad Rakha, Nasir Rajpoot   +16 more
doaj   +1 more source

Wireless Heart Sensor for Capturing Cardiac Orienting Response for Prediction of Neurodevelopmental Delay in Infants

Sensors, 2022
Early identification of infants at risk of neurodevelopmental delay is an essential public health aim. Such a diagnosis allows early interventions for infants that maximally take advantage of the neural plasticity in the developing brain.
Marcelo Aguilar-Rivera, Julie A. Kable, Lyubov Yevtushok, Yaroslav Kulikovsky, Natalya Zymak-Zakutnya, Iryna Dubchak, Diana Akhmedzhanova, Wladimir Wertelecki, Christina Chambers, Todd P. Coleman   +9 more
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li, Raquel Revuelta Iniesta, Alan R. Barker, Dimitris Vlachopoulos, Tomáš Sláma, Christina Schindera, Fabiën N. Belle   +6 more
wiley   +1 more source

Assessment and Management of Pain in Preterm Infants: A Practice Update

Children, 2022
Infants born preterm are at a high risk for repeated pain exposure in early life. Despite valid tools to assess pain in non-verbal infants and effective interventions to reduce pain associated with medical procedures required as part of their care, many ...
Marsha Campbell-Yeo, Mats Eriksson, Britney Benoit   +2 more
doaj   +1 more source

Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]

, 2016
Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core   +2 more sources

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan, Damien Faury, Alexander G. Weil, Harrison J. Westwick, Nada Jabado, Sébastien Perreault   +5 more
wiley   +1 more source

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup. [PDF]

, 2017
Purpose: Current clinical parameters do not stratify indolent from aggressive prostate cancer. Aggressive prostate cancer, defined by the progression from localized disease to metastasis, is responsible for the majority of prostate cancer–associated ...
Alshalalfa, Mohammed,, Bowden, Michaela,, Brown, Myles,, Davicioni, Elai,, Den, Robert B.,, Ellis, Leigh,, Eng, Kevin H.,, Erho, Nicholas,, Feng, Felix Y.,, Galbo, Phillip,, Goodrich, David W.,, Gray, Kathryn P.,, Huang, Ying,, Jenkins, Robert B.,, Karnes, R. Jeffrey,, Ku, Sheng Yu,, Labbé, David P.,, Lund University., Rosario, Spencer,, Ross, Ashley E., Schaeffer, Edward M.,, Sjöström, Martin,, Spratt, Daniel E.,, Sweeney, Christopher J.,, Wadosky, Kristine M.,   +24 more
core   +2 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Willingness to pay for osteoporosis risk assessment in primary dental care

Health Economics Review, 2019
Background Fragility fracture related to osteoporosis among postmenopausal women is a significant cause of morbidity. The care and aftercare of these fractures are associated with substantial costs to society.
Helena Christell, Joanna Gullberg, Kenneth Nilsson, Sofia Heidari Olofsson, Christina Lindh, Thomas Davidson   +5 more
doaj   +1 more source