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Aging Leads to Poor Outcome after Subarachnoid Hemorrhage through Exacerbating Early Brain Injury [PDF]

Neurologia Medico-Chirurgica
Early brain injury after a subarachnoid hemorrhage is an important prognostic factor. Aging is also an important prognostic factor of subarachnoid hemorrhage. However, the association between early brain injury and aging remains unclear.
Tomofumi TAKENAKA, Masatoshi TAKAGAKI, Hajime NAKAMURA, Takeo NISHIDA, Masaaki TANIGUCHI, Akihiro TATEISHI, Maki KOBAYASHI, Shogo FUKUYA, Tomoaki MURAKAMI, Takeshi SHIMIZU, Takamune ACHIHA, Yuichi MATSUI, Shuhei YAMADA, Tatsumaru FUKUDA, Ryota NAKAGAWA, Takaki MATSUMURA, Hidekazu NAKATA, Yuhei HOSHIKUMA, Shingo TOYOTA, Akatsuki WAKAYAMA, Haruhiko KISHIMA   +20 more
doaj   +2 more sources

White Matter Injury in Early Brain Injury after Subarachnoid Hemorrhage [PDF]

Cell Transplantation, 2019
Subarachnoid hemorrhage (SAH) is a major cause of high morbidity, disability, and mortality in the field of neurovascular disease. Most previous SAH studies have focused on improving cerebral blood flow, reducing cerebral vasospasm, reducing neuronal ...
Jinwei Pang, Jianhua Peng, Ping Yang, Li Kuai, Ligang Chen, John H. Zhang, Yong Jiang   +6 more
doaj   +3 more sources

Ferroptosis in early brain injury after subarachnoid hemorrhage: review of literature [PDF]

Chinese Neurosurgical Journal
Spontaneous subarachnoid hemorrhage (SAH), mainly caused by ruptured intracranial aneurysms, is a serious acute cerebrovascular disease. Early brain injury (EBI) is all brain injury occurring within 72 h after SAH, mainly including increased intracranial
Junlin Kang, Shilai Tian, Lei Zhang, Gang Yang   +3 more
doaj   +2 more sources

Traumatic Injury to the Developing Brain: Emerging Relationship to Early Life Stress

Frontiers in Neurology, 2021
Despite the high incidence of brain injuries in children, we have yet to fully understand the unique vulnerability of a young brain to an injury and key determinants of long-term recovery.
Kaila N. Parker, Kaila N. Parker, Michael H. Donovan, Michael H. Donovan, Kylee Smith, Kylee Smith, Linda J. Noble-Haeusslein, Linda J. Noble-Haeusslein   +7 more
doaj   +1 more source

Marshall Computed Tomography Scoring System in Predicting Early Mortality in Patients with Traumatic Brain Injury

Journal of Nepal Health Research Council, 2022
Background: Traumatic brain injury is common neurological emergency worldwide associated with high rates of morbidity and mortality. Marshall scoring system is one of the several scoring systems that uses initial computed tomography findings to predict ...
Akash Chitrakar, Binod Rajbhandari, Gopal Sedain, Amit Bahadur Pradhananga, Mohan Raj Sharma   +4 more
doaj   +1 more source

Early myoclonus following anoxic brain injury [PDF]

Neurology Clinical Practice, 2018
It is unknown whether postanoxic cortical and subcortical myoclonus are distinct entities with different prognoses.In this retrospective cohort study of 604 adult survivors of cardiac arrest over 8.5 years, we identified 111 (18%) patients with myoclonus. Basic demographics and clinical characteristics of myoclonus were collected.
Reynolds, Alexandra, Rohaut, Benjamin, Holmes, Manisha, Robinson, David, Roth, William, Velazquez, Angela, Couch, Caroline, Presciutti, Alex, Brodie, Daniel, Moitra, Vivek, Rabbani, Leroy, Agarwal, Sachin, Park, Soojin, Roh, David, Claassen, Jan   +14 more
openaire   +2 more sources

Early neuro-rehabilitation in traumatic brain injury: the need for an African perspective

BMC Medicine, 2023
Background Traumatic brain injury (TBI) is a global public health challenge, affecting about 69 million individuals annually and being one of the leading causes of mortality.
Franklin Chu Buh, Peter J. A. Hutchinson, Fahim Anwar   +2 more
doaj   +1 more source

Depolarization time and extracellular glutamate levels aggravate ultraearly brain injury after subarachnoid hemorrhage

Scientific Reports, 2022
Early brain injury after aneurysmal subarachnoid hemorrhage (SAH) worsens the neurological outcome. We hypothesize that a longer duration of depolarization and excessive release of glutamate aggravate neurological outcomes after SAH, and that brain ...
Satoshi Murai, Tomohito Hishikawa, Yoshimasa Takeda, Yasuko Okura, Miki Fushimi, Hirokazu Kawase, Yu Takahashi, Naoya Kidani, Jun Haruma, Masafumi Hiramatsu, Kenji Sugiu, Hiroshi Morimatsu, Isao Date   +12 more
doaj   +1 more source

Inflammatory role of microglia in brain injury caused by subarachnoid hemorrhage

Frontiers in Cellular Neuroscience, 2022
Early brain injury is a series of pathophysiological changes and direct damage of brain tissue within 72 h after subarachnoid hemorrhage before cerebral vasospasm occurs.
Xiao-Yi Wang, Fan Wu, Ren-Ya Zhan, Heng-Jun Zhou   +3 more
doaj   +1 more source

Brain interrupted: Early life traumatic brain injury and addiction vulnerability [PDF]

Experimental Neurology, 2019
Recent reports provide evidence for increased risk of substance use disorders (SUD) among patients with a history of early-life traumatic brain injury (TBI). Preclinical research utilizing animal models of TBI have identified injury-induced inflammation, blood-brain barrier permeability, and changes to synapses and neuronal networks within regions of ...
Lee Anne, Cannella, Hannah, McGary, Servio H, Ramirez   +2 more
openaire   +2 more sources