Results 101 to 110 of about 23,513,968 (309)

Early Social-Emotional and Cognitive Basis for Human Development Potential, and Improved Quality of Life

, 2007
This presentation discusses the effects of social motivation on brain development in early childhood and the role of emotions on child development. Optimal nutrition and social-emotional development are the basic building blocks for higher level thinking
Inter-American Development Bank
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Play in the digital age: linking preschool children’s digital play addiction tendency, parental mediation strategies, and classroom playfulness

Frontiers in Psychology
IntroductionDigital play occupies a prominent place in young children’s daily lives. However, limited evidence exists on how parental mediation of digital play relates to children’s observed playfulness in non-digital environments and their digital play ...
Berna Sicim Sevim, Sırma Seda Bapoğlu Dümenci   +1 more
doaj   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

The Early Years: Child Well-being and the Role of Public Policy

, 2015
Child well-being matters for both ethical and economic reasons as children who flourish in the early years are more likely to become healthy, productive citizens later in life.
Inter-American Development Bank
core   +1 more source

Preschool Teachers’ Attitudes about Inclusive Education and Its Influencing Factors in China

Behavioral Sciences
Background/Objectives: The purpose of this study is to describe the current status of preschool teachers’ attitudes about inclusive education and discuss the factors that influence these attitudes.
Xiaomei Peng, Toby Long, Xueyun Su
doaj   +1 more source

What can functional transcranial Doppler ultrasonography reveal about the cerebral lateralization of writing

FEBS Letters, EarlyView.
Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley   +1 more source

Early Childhood Development: Wealth, the Nurturing Environment and Inequality First Results from the PRIDI Database [PDF]

, 2016
This paper presents findings from the Regional Project on Child Development Indicators, PRIDI for its acronym in Spanish. PRIDI created a new tool, the Engle Scale, for evaluating development in children aged 24 to 59 months in four domains: cognition ...
Inter-American Development Bank
core   +1 more source