Results 151 to 160 of about 1,193,465 (362)

‘There are plenty of opportunities for play and learning’ – Swedish preschool teachers’ perspectives on using the outdoor environment as a pedagogical resource

open access: yesCogent Education
This study examines five preschool teachers’ narratives about using the outdoor environment as a pedagogical resource for children’s play, learning and experiences in Swedish preschools.
Ester Catucci   +2 more
doaj   +1 more source

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

open access: yesAdvanced Science, EarlyView.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng   +22 more
wiley   +1 more source

Long-Term Effects of Early Childhood Care and Education [PDF]

open access: yes
This paper critically reviews what we know about the long-term effects of parental leave and early childhood education programs. We find only limited evidence that expansions of parental leave durations improved long-run educational or labor market ...
Ruhm, Christopher J., Waldfogel, Jane
core  

Developmental Education: The Value of High Quality Preschool Investments as Economic Tools [PDF]

open access: yes, 2004
This working paper is among a series of papers funded by the Pew Charitable Trusts through its "Advancing Quality Pre-K for All" initiative. The paper finds that early childhood education appears to offer great potential returns and low risks, and should

core  

Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells

open access: yesAdvanced Science, EarlyView.
Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser   +20 more
wiley   +1 more source

Variations in Innate Immune Cell Subtypes Correlate with Epigenetic Clocks, Inflammaging and Health Outcomes

open access: yesAdvanced Science, EarlyView.
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo   +17 more
wiley   +1 more source

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