Results 31 to 40 of about 1,184,483 (342)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Cross-lagged relationship between home numeracy practices and early mathematical skills among Chinese young children

open access: yesFrontiers in Psychology, 2022
The present study examined the cross-lagged relationship between home numeracy practices (e.g., formal teaching, number games, and number application) and early mathematical skills (basic number processing, and arithmetic skills) among Chinese young ...
Wei Wei   +5 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Co-parenting, parental competence and problem behaviours in children: examining differential parental roles

open access: yesHumanities & Social Sciences Communications
In recent years, the increase in child problem behaviours has become a significant public health concern. It is crucial to understand the complex dynamics between parental co-parenting, parenting competence, and child problem behaviours to develop ...
Baocheng Pan   +6 more
doaj   +1 more source

IMPLEMENTASI PEMBERDAYAAN KELUARGA MELALUI PENDIDIKAN ANAK USIA DINI PADA POS PEMBERDAYAAN KELUARGA DI DUSUN SAMAN DESA BANGUNHARJO KECAMATAN SEWON KABUPATEN BANTUL [PDF]

open access: yes, 2011
This study aims to describe: (1) Implementation Process empowering families through early childhood education at Posdaya, (2) The benefits of early childhood for the Saman’s people, (3) supporting and obstacles factors in the implementation of early ...
Kristinah Prasetia Ningsih, Kristinah Prasetia Ningsih
core  

Non-parental caregivers, parents, and the school readiness of the children of Latino/a immigrants [PDF]

open access: yes, 2017
School readiness generally predicts trajectories of academic achievement over time, motivating efforts to support the development of school readiness skills by expanding access to and improving the quality of early childhood care and education.
Pivnick, Lilla Kármán
core   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

The complex longitudinal influence of paternal and maternal parental psychological flexibility on child problem behavior: exploring the role of parenting styles

open access: yesBMC Psychology
Purpose This study aims to explore the complex relationship between paternal and maternal parental psychological flexibility, parenting styles, and child problem behavior within the cultural context of China. Methods Structural equation modeling was used
Baocheng Pan   +6 more
doaj   +1 more source

Early Developmental Activities and Computing Proficiency [PDF]

open access: yes, 2018
As countries adopt computing education for all pupils from primary school upwards, there are challenging indicators: significant proportions of students who choose to study computing at universities fail the introductory courses, and the evidence for ...
Alshaigy, Bedour   +9 more
core   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

open access: yesMolecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová   +14 more
wiley   +1 more source

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