Results 91 to 100 of about 4,076,951 (295)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Egyptian Journal of Radiology and Nuclear MedicineBackground Fibroadenomas are benign breast tumors composed of epithelial and stromal tissue. While most have consistent imaging features and are considered simple fibroadenomas, several histological variants exist.
Sherihan Fakhry +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Herschel Virgo Cluster Survey. VII. Dust in cluster dwarf elliptical galaxies [PDF]
, 2010 We use the science demonstration phase data of the Herschel Virgo Cluster Survey to search for dust emission of early-type dwarf galaxies in the central regions of the Virgo cluster as an alternative way of identifying the interstellar medium. We present
De Looze, I., Fadda, D.
core
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Child development - issues in early detection [PDF]
Child development is a complex, non-linear process affected by multiple factors. In addition, there is a large degree of individual variation. Developmental delay is present when a child does not reach developmental milestones at the expected age (with ...
Frank Oberklaid, Martin Wright
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Nature CommunicationsEarly therapeutic intervention in high-risk smoldering multiple myeloma (HR-SMM) has shown benefits, however, no studies have assessed whether biochemical progression or response depth predicts long-term outcomes.
Omar Nadeem +21 more
doaj +1 more source
Early Detection of Emphysema Progression [PDF]
, 2010 Emphysema is one of the most widespread diseases in subjects with smoking history. The gold standard method for estimating the severity of emphysema is a lung function test, such as forced expiratory volume in first second (FEV1). However, several clinical studies showed that chest CT scans offer more sensitive estimates of emphysema progression.
Gorbunova, Vladlena +6 more
openaire +4 more sources