Results 71 to 80 of about 9,208,125 (300)

Modeling and detection of hydrodynamic trends for advancing early-tsunami warnings

, 2013
The automated detection of tsunamigenic signals at oceanic observation stations is highly desirable for the advancement of current tsunami early warning systems.
Lowe, Peter, Tinti, Stefano, Wachter, Joachim, Hammitzsch, Martin, Arbab-Zavar, Banafshe, Armigliato, Alberto, Pagnoni, Gianluca, Sabeur, Zoheir, Omira, Rachid, Lendholdt, Matthias   +9 more
core   +1 more source

A Computationally Guided Approach to Improve Expression of VHH Binders

Biophysica
The variable heavy chain fragments derived from camelid antibodies, called VHHs or nanobodies, have recently shown promise as high-affinity reagents. They offer higher stability compared to conventional antibodies and fragments thereof.
Emine Sila Ozdemir, Jessica Tolley, Florian Goncalves, Michelle Gomes, Eli Wagnell, Bruce Branchaud, Viktoriya Dubrovskaya, Srivathsan V. Ranganathan   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Early hearing detection and intervention [PDF]

Department of Health and Human Services, Centers for Disease Control and Prevention."Safer-healthier-people" --Cover.Produced by the CDC's National Center on Birth Defects and Developmental Disabilities Early Hearing Detection and Intervention Program ...

core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Guía de recursos para familias

, 2009
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Jan.

core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Integrated Forest Monitoring System for Early Fire Detection and Assessment

, 2019
This paper presents a novel system for automatic early detection of wild forest-fire using optical and thermal cameras at ground station and mounted on Unmanned Aerial Systems (UAS).
Loizou, Savvas, Papageorgiou, Xanthi, Georgiades, George P.   +2 more
core   +1 more source

Improved sex-specific cardiovascular risk prediction with multi-omics data in people with type 2 diabetes

Cardiovascular Diabetology
Background To evaluate whether integrating proteomics, metabolomics, and a cardiovascular disease specific polygenic risk score (CVD-PRS) in the SCORE2-Diabetes model improves sex-specific 10-year prediction of major adverse cardiovascular events (MACE ...
Ruijie Xie, Christian Herder, Sha Sha, Hermann Brenner, Sigrid Carlsson, Ben Schöttker   +5 more
doaj   +1 more source