Results 111 to 120 of about 1,409,842 (340)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Mutation of the peptide-regulated transcription factor ComR for amidated peptide specificity and heterologous function in Lactiplantibacillus plantarum WCFS1

Microbiology Spectrum
There is a growing interest in the use of probiotic bacteria as biosensors for the detection of disease. However, there is a lack of bacterial receptors developed for specific disease biomarkers.
Michael Brasino, Eli Wagnell, E. Sila Ozdemir, Srivathsan Ranganathan, Justin Merritt   +4 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Retraction Note to: Clinical significance and expression of the PRSS3 and Wiskott–Aldrich syndrome protein family verprolin-homologous protein 1 for the early detection of epithelial ovarian cancer [PDF]

, 2016
Sima Azizmohammadi, Aghdas Safari, Mehri Seifoleslami, Rahman Ghaffarzadegan Rabati, Mohsen Mohammadi, Hamid Yahaghi, Susan Azizmohammadi   +6 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Pilot Study of 64Cu(I) for PET Imaging of Melanoma

Scientific Reports, 2017
At present, 64Cu(II) labeled tracers including 64CuCl2 have been widely applied in the research of molecular imaging and therapy. Human copper transporter 1 (hCTR1) is the major high affinity copper influx transporter in mammalian cells, and specially ...
Lei Jiang, Yingfeng Tu, Xiang Hu, Ande Bao, Hao Chen, Xiaowei Ma, Tim Doyle, Hongcheng Shi, Zhen Cheng   +8 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Barriers and contributions of rural community health workers in enabling cancer early detection and subsequent care in India: a qualitative study

BMC Public Health
Background The cancer burden in India is escalating, with rural regions facing the greatest challenges in access to early detection and treatment. Community Health Workers (CHWs), such as Accredited Social Health Activists (ASHAs), Village Health Nurses (
Sathishrajaa Palaniraja, Katayoun Taghavi, Ishu Kataria, Kunal Oswal, Nandimandalam Venkata Vani, Asiya Ansari Liji, Hardika Parekh, Rita Isaac, Moni Kuriakose, Rajaraman Swaminathan, Rohit Rebello, Arnie Purushotham, Partha Basu, Richard Sullivan, Arunah Chandran   +14 more
doaj   +1 more source

Biomarkers for Early Detection of Cancer: Molecular Aspects. [PDF]

Int J Mol Sci, 2023
Tappia PS, Ramjiawan B.
europepmc   +1 more source

Hubungan Pengetahuan dan Sikap terhadap Tindakan Wanita Pekerja Seksual Tidak Langsung Tentang Pap Smear dan Iva sebagai Deteksi Dini Kanker Serviks di Hotspot X Kecamatan Payung Sekaki Pekanbaru [PDF]

, 2016
Cervical cancer is a Malignant cell which lives in cervical cells. Cervicalcancer is in the second most common cancer after breast cancer in Indonesia.Based on the fact, indirect female sex worker have high risk factor of gettingcervical cancer.
Fidiawati, W. A. (Wiwit), Suyanto, S. (Suyanto), Syahputra, E. (Erwin)   +2 more
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