Results 51 to 60 of about 773,646 (162)

Predicting colorectal cancer survival by combined c-reactive protein and tumor immune score

npj Precision Oncology
We evaluated the joint relationship of post-operative C-reactive protein (poCRP) and a tumor immune-cell-score (IS) with overall survival (OS) and CRC-specific survival (CSS) in 680 colorectal cancer (CRC) patients recruited in Germany.
Tafirenyika Gwenzi, Durgesh Wankhede, Tanwei Yuan, Megha Bhardwaj, Petra Schrotz-King, Sophie C. Anker, Ben Schöttker, Michael Hoffmeister, Hermann Brenner   +8 more
doaj   +1 more source

Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer

Biomarker Research, 2017
Background Quantitative proteomics allows for the discovery and functional investigation of blood-based pre-diagnostic biomarkers for early cancer detection.
Christine Y. Yeh, Ravali Adusumilli, Majlinda Kullolli, Parag Mallick, Esther M. John, Sharon J. Pitteri   +5 more
doaj   +1 more source

Deeper response predicts better outcomes in high-risk-smoldering-myeloma: results of the I-PRISM phase II clinical trial

Nature Communications
Early therapeutic intervention in high-risk smoldering multiple myeloma (HR-SMM) has shown benefits, however, no studies have assessed whether biochemical progression or response depth predicts long-term outcomes.
Omar Nadeem, Michelle P. Aranha, Robert Redd, Michael Timonian, Sophie Magidson, Elizabeth D. Lightbody, Jean-Baptiste Alberge, Luca Bertamini, Ankit K. Dutta, Habib El-Khoury, Mark Bustoros, Jacob P. Laubach, Giada Bianchi, Elizabeth O’Donnell, Ting Wu, Junko Tsuji, Kenneth C. Anderson, Gad Getz, Lorenzo Trippa, Paul G. Richardson, Romanos Sklavenitis-Pistofidis, Irene M. Ghobrial   +21 more
doaj   +1 more source

Imaging features for distinguishing simple and complex fibroadenomas of the breast: a retrospective observational study

The Egyptian Journal of Radiology and Nuclear Medicine
Background Fibroadenomas are benign breast tumors composed of epithelial and stromal tissue. While most have consistent imaging features and are considered simple fibroadenomas, several histological variants exist.
Sherihan Fakhry, Ola Mohamed Saeed Abdelhalim Aboulnour, Enas Mohamed Mustafa Sweed   +2 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology
Screening heavy smokers by low‐dose computed tomography (LDCT) can reduce lung cancer (LC) mortality, but defining the population that benefits most, a prerequisite for cost‐effective screening, is challenging.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
doaj   +1 more source

Assessment of barriers to the cervical cancer continuum and existing interventions in 5 African countries

BMC Public Health
Background Several studies have been conducted in Africa on barriers to cervical cancer screening from the individual and the healthcare professional perspective, while the existing interventions to overcome these barriers have been seldom reported.
Isabel Mosquera, Arunah Chandran, Mary Luz Rol, Adie Yao Mesmin Olivier, Yacubu Bakare Herve Julius, Takelech Moges Asnake, Frank Rwabinumi Mugabe, Bridget Kebirungi, Mwate Joseph Chaila, George Pupwe, Bothwell Takaingofa Guzha, Ndabaningi Simango, Sharon Kapambwe, Jean Marie Dangou, Partha Basu, Andre Lopes Carvalho   +15 more
doaj   +1 more source

Epigenetic indicators of body mass predict survival outcomes in colorectal cancer patients: patient cohort analysis

Genome Medicine
Background The prognostic relevance of body mass index (BMI) in colorectal cancer (CRC) remains controversial, partly due to disease-related weight loss.
Tanwei Yuan, Marko Mandic, Xianzhe Li, Melanie Bewerunge-Hudler, Hermann Brenner, Michael Hoffmeister   +5 more
doaj   +1 more source

Micropapillary breast carcinoma in comparison with invasive duct carcinoma. Does it have an aggressive clinical presentation and an unfavorable prognosis?

BMC Cancer
Background Invasive micropapillary carcinoma (IMPC) was first proposed as an entity by Fisher et al. In the 2003 World Health Organization (WHO) guidelines for histologic classification of the breast tumors.
Yasmine Hany Abdel Moamen Elzohery, Amira H. Radwan, Sherihan W. Y. Gareer, Mona M. Mamdouh, Inas Moaz, Abdelrahman Mohammad Khalifa, Osama Abdel Mohen, Mohamed Fathy Abdelfattah Abdelrahman Elithy, Mahmoud Hassaan   +8 more
doaj   +1 more source

Multiplex imaging of localized prostate tumors reveals altered spatial organization of AR-positive cells in the microenvironment

iScience
Summary: Mapping the spatial interactions of cancer, immune, and stromal cell states presents novel opportunities for patient stratification and for advancing immunotherapy.
Çiğdem Ak, Zeynep Sayar, Guillaume Thibault, Erik A. Burlingame, M.J. Kuykendall, Jennifer Eng, Alex Chitsazan, Koei Chin, Andrew C. Adey, Christopher Boniface, Paul T. Spellman, George V. Thomas, Ryan P. Kopp, Emek Demir, Young Hwan Chang, Vasilis Stavrinides, Sebnem Ece Eksi   +16 more
doaj   +1 more source

Interval breast cancer: radiological surveillance in screening Egyptian population

The Egyptian Journal of Radiology and Nuclear Medicine
Background Interval cancers might be divided into true negative interval cancer where a new lesion is detected that no sign of disease could be detected on previous screening mammogram. For false-negative interval cancers, those missed for overt symptoms
Ola Magdy Mohamed Shetat, Mai Magdy Abdelmonem Abdelaal, Dalia Hussein, Mohamed Fahim, Eman Faker Mokhtar Kamal   +4 more
doaj   +1 more source