Results 31 to 40 of about 773,646 (162)
Early detection of ovarian cancer [PDF]
Abstract Early detection is the only way to achieve a high cure rate in women with ovarian cancer. Unfortunately, to date, there is no effective strategy for early detection, despite rapidly emerging biomarkers. The low prevalence of ovarian cancer, low specificity and high rates of false positives have been limitations of screening programs.
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Background Therapeutic strategies engaging the immune system against malignant cells have revolutionized the field of oncology. Proficiency of dendritic cells (DCs) for antigen presentation and immune response has spurred interest on DC-based vaccines ...
Natacha Jugniot +2 more
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Early Detection of Ovarian Cancer [PDF]
Despite advances in therapy, ovarian cancer remains the most deadly of the gynecological cancers. Less than 30% of women with advanced stage disease survive long‐term. When diagnosed in stage I, up to 90% of patients can be cured with conventional surgery and chemotherapy. At present, only 25% of ovarian cancers are detected in stage I due, in part, to
Badgwell, Donna, Bast Jr., Robert C.
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Early detection of pancreatic cancer
Purpose of review Pancreatic cancer is the third leading cause of cancer death and with a dismal 5-year survival of 10%. Poor survival of pancreatic cancer is mostly due to its presentation and diagnosis at a late stage. The present article aims to update clinicians with recent progress in the field of early detection of ...
Sushil Kumar, Garg, Suresh T, Chari
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Interpretable and integrative analysis of single-cell multiomics with scMKL
The rapid advancement of single-cell technologies has led to the development of various analysis methods, each with trade-offs between predictive power and interpretability particularly for multimodal data integration.
Samuel D. Kupp +5 more
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Can computed tomography predict nodal metastasis in breast cancer patients?
Background Axillary lymph node metastasis is considered one of the main prognostic factors clinically used for the evaluation of breast cancer patient.
Sherihan Fakhry +3 more
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Early Detection of Pancreatic Cancer
Despite treatment advances pancreatic cancer remains one of the most lethal malignancies. It is expected that early detection and screening of high risk patient population may have the most significant impact on altering overall survival in this disease. Serologic biomarkers may be the most useful in early detection and histology-based markers may have
Vasco, Eguia +2 more
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Early Detection of Cancer: An Overview [PDF]
There are two types of preventive services: primary prevention acts to reduce the probability of disease before its onset by decreasing exposure to risk factors; secondary prevention (early detection) identifies the disease at an early stage so that effective treatment can be administered sooner than would have otherwise been possible.
R N, Battista, S A, Grover
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Early detection of lung cancer [PDF]
Most patients with lung cancer are diagnosed when they present with symptoms, they have advanced stage disease, and curative treatment is no longer an option. An effective screening test has long been desired for early detection with the goal of reducing mortality from lung cancer.
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Daratumumab in high-risk MGUS and low-risk smoldering myeloma: results of the Phase II D-PRISM study
Daratumumab is approved for patients with multiple myeloma (MM) and high-risk smoldering MM (HR-SMM). However, HR-SMM is often as genomically complex as MM, suggesting it may be too advanced for single-agent intervention. We report on a Phase II trial of
Omar Nadeem +32 more
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