Results 21 to 30 of about 813,162 (218)

Cancer burden and status of cancer control measures in fragile states: a comparative analysis of 31 countries

The Lancet Global Health, 2022
Summary: Background: Information on cancer statistics and cancer control policies is limited in fragile states. This paper describes the cancer burden and status of cancer control measures in these countries.
Isabel Mosquera, PhD, Andre Ilbawi, PhD, Richard Muwonge, PhD, Partha Basu, MD, Andre L Carvalho, MD   +4 more
doaj   +1 more source

Molecular triaging options for women testing HPV positive with self-collected samples

Frontiers in Oncology, 2023
We review developments in molecular triaging options for women who test positive for high-risk human papillomavirus (hrHPV) on self-collected samples in the context of cervical cancer elimination.
Katayoun Taghavi, Fanghui Zhao, Laura Downham, Armando Baena, Partha Basu   +4 more
doaj   +1 more source

The combined effect of socioeconomic status and metabolic syndrome on depression: the Korean National Health and Nutrition Examination Survey (KNHANES)

BMC Public Health, 2020
Background Depression shows different patterns depending on socioeconomic status (SES) and metabolic syndrome (MS). However, the nature of this association remains poorly understood.
B. Kim, E. Y. Park
doaj   +1 more source

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

EBioMedicine, 2021
Background: Senescent cells accumulate in tissues over time as part of the natural ageing process and the removal of senescent cells has shown promise for alleviating many different age-related diseases in mice.
Hillary H. Le, Suleyman S. Cinaroglu, Elise C. Manalo, Aysegul Ors, Michelle M. Gomes, Burcin Duan Sahbaz, Karla Bonic, Carlos A. Origel Marmolejo, Arnaud Quentel, Justin S. Plaut, Taryn E. Kawashima, E. Sila Ozdemir, Sanjay V. Malhotra, Yavuz Ahiska, Ugur Sezerman, Gunseli Bayram Akcapinar, Joshua C. Saldivar, Emel Timucin, Jared M. Fischer   +18 more
doaj   +1 more source

Immunotheranostic microbubbles (iMBs) - a modular platform for dendritic cell vaccine delivery applied to breast cancer immunotherapy

Journal of Experimental & Clinical Cancer Research, 2022
Background Therapeutic strategies engaging the immune system against malignant cells have revolutionized the field of oncology. Proficiency of dendritic cells (DCs) for antigen presentation and immune response has spurred interest on DC-based vaccines ...
Natacha Jugniot, Jeremy J. Dahl, Ramasamy Paulmurugan   +2 more
doaj   +1 more source

Interpretable and integrative analysis of single-cell multiomics with scMKL

Communications Biology
The rapid advancement of single-cell technologies has led to the development of various analysis methods, each with trade-offs between predictive power and interpretability particularly for multimodal data integration.
Samuel D. Kupp, Ian A. VanGordon, Mehmet Gönen, Sadık Esener, Sebnem Ece Eksi, Çiğdem Ak   +5 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Daratumumab in high-risk MGUS and low-risk smoldering myeloma: results of the Phase II D-PRISM study

Nature Communications
Daratumumab is approved for patients with multiple myeloma (MM) and high-risk smoldering MM (HR-SMM). However, HR-SMM is often as genomically complex as MM, suggesting it may be too advanced for single-agent intervention. We report on a Phase II trial of
Omar Nadeem, Michelle P. Aranha, Robert A. Redd, Michael Koontz, Jeffrey V. Matous, Andrew J. Yee, Jeffrey A. Zonder, Andrew Kin, Sophie Magidson, Elizabeth D. Lightbody, Ting Wu, Floris Chabrun, Jean-Baptiste Alberge, Ankit K. Dutta, Jacqueline Perry, Ashlee Sturtevant, Mahshid Rahmat, Junko Tsuji, Christine Davie, Caroline Ricciardi, Frances Arters, Marjorie Marto, Amy Bergeron, Jacalyn Rosenblatt, Elizabeth K. O’Donnell, Tarek H. Mouhieddine, Lorena Pantano, Jacob P. Laubach, Paul G. Richardson, Gad Getz, Lorenzo Trippa, Romanos Sklavenitis-Pistofidis, Irene M. Ghobrial   +32 more
doaj   +1 more source