Results 21 to 30 of about 1,392,284 (290)

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

open access: yesEBioMedicine, 2021
Background: Senescent cells accumulate in tissues over time as part of the natural ageing process and the removal of senescent cells has shown promise for alleviating many different age-related diseases in mice.
Hillary H. Le   +18 more
doaj   +1 more source

Media Coverage of the Benefits and Harms of Testing the Healthy: A protocol for a descriptive study [PDF]

open access: yes, 2019
INTRODUCTION: Much testing in medicine is aimed at healthy people to facilitate the early detection of health conditions. However, there is growing evidence that early detection is a double-edged sword that may cause harm in the form of overdiagnosis ...
Barratt, Alexandra   +6 more
core   +1 more source

Detection of early lung cancer [PDF]

open access: yesThorax, 2000
Background. The Early Lung Cancer Action Project (ELCAP) is designed to evaluate baseline and annual repeat screening by low-radiation-dose computed tomography (low-dose CT) in people at high risk of lung cancer. We report the baseline experience. Methods.
J C, Porter, S G, Spiro
openaire   +2 more sources

Tyrol Prostate Cancer Demonstration Project : early detection, treatment, outcome, incidence and mortality [PDF]

open access: yes, 2008
This study aimed to evaluate the effectiveness of a well-controlled programme of early detection and treatment of prostate cancer in the population of Tyrol, Austria, where such a programme of early detection and treatment was initiated in 1988 and where
Bartsch, Georg   +13 more
core   +1 more source

Novel nano-biosensors for life science systems and their applications in early, accurate, and non-invasive melanoma and other types of cancer detection [PDF]

open access: yes, 2007
Melanoma (the 5th and 6th most common cancer in Caucasian males and females, respectively), is the most severe form of skin cancer, which is often fatal if recognized in its advanced stage.
Bockrath, Marc   +2 more
core   +1 more source

Breast tumor diagnosis in digital mammograms [PDF]

open access: yes, 2019
Breast cancer has been classified as the most common cancer in most part of the world [1]. Breast cancer is caused by the growth of the abnormal cells in the breast. Breast cancer not only develops in women but also on men.
Gaik Tay, Kim   +2 more
core   +1 more source

Novel mutations in the BRCA1 and BRCA2 genes in Iranian women with early-onset breast cancer [PDF]

open access: yes, 2002
BACKGROUND: Breast cancer is the most common female malignancy and a major cause of death in middle-aged women. So far, germline mutations in the BRCA1 and BRCA2 genes in patients with early-onset breast and/or ovarian cancer have not been identified
Dalton, Ann   +6 more
core   +2 more sources

Immunotheranostic microbubbles (iMBs) - a modular platform for dendritic cell vaccine delivery applied to breast cancer immunotherapy

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background Therapeutic strategies engaging the immune system against malignant cells have revolutionized the field of oncology. Proficiency of dendritic cells (DCs) for antigen presentation and immune response has spurred interest on DC-based vaccines ...
Natacha Jugniot   +2 more
doaj   +1 more source

Microbiota, Oral Microbiome, and Pancreatic Cancer [PDF]

open access: yes, 2014
Only 30% of patients diagnosed with pancreatic cancer survive one year post-diagnosis. Progress in understanding the causes of pancreatic cancer has been made, including solidifying the associations with obesity and diabetes, and a proportion of cases ...
Izard, Jacques, Michaud, Dominique S.
core   +2 more sources

Early Detection of Pancreatic Cancer

open access: yesJOP : Journal of the pancreas, 2012
Despite treatment advances pancreatic cancer remains one of the most lethal malignancies. It is expected that early detection and screening of high risk patient population may have the most significant impact on altering overall survival in this disease. Serologic biomarkers may be the most useful in early detection and histology-based markers may have
Vasco, Eguia   +2 more
openaire   +2 more sources

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