Results 21 to 30 of about 2,379,974 (319)

Early Infant Diagnosis of HIV in Three Regions in Tanzania; Successes and Challenges. [PDF]

, 2013
By the end of 2009 an estimated 2.5 million children worldwide were living with HIV-1, mostly as a consequence of vertical transmission, and more than 90% of these children live in sub-Saharan Africa.
Bygbjerg, Ib Christian, Lemnge, Martha M., Mmbando, Bruno P, Chiduo, Mercy G., Theilgaard, Zarah P., Gerstoft, Jan, Jan Gerstoft, Bruno P Mmbando, Katzenstein, Terese, Lemnge, Martha, Mercy G Chiduo, Ib C Bygbjerg, Terese L Katzenstein, Chiduo, Mercy G, Zahra P Theilgaard, Mmbando, Bruno M., Martha Lemnge, Theilgaard, Zahra P, Katzenstein, Terese L, Bygbjerg, Ib C   +19 more
core   +1 more source

Macrolide Therapy in Chronic Inflammatory Diseases

Mediators of Inflammation, 2012
Macrolides are a group of antibiotics with a distinctive macrocyclic lactone ring combined with sugars (cladinose, desosamine). The action of macrolides is to block protein synthesis by binding to the subunit of 50S ribosome of bacteria.
Brygida Kwiatkowska, Maria Maślińska
doaj   +1 more source

A Novel Model Based on Genomic Instability-Associated Long Non-Coding RNAs for Predicting Prognosis and Response to Immunotherapy in Patients With Lung Adenocarcinoma

Frontiers in Genetics, 2021
Background: Emerging scientific evidence has shown that long non-coding RNAs (lncRNAs) exert critical roles in genomic instability (GI), which is considered a hallmark of cancer. To date, the prognostic value of GI-associated lncRNAs (GI-lncRNAs) remains
Guangxu Tu, Guangxu Tu, Weilin Peng, Weilin Peng, Qidong Cai, Qidong Cai, Zhenyu Zhao, Zhenyu Zhao, Xiong Peng, Xiong Peng, Boxue He, Boxue He, Pengfei Zhang, Pengfei Zhang, Shuai Shi, Shuai Shi, Xiang Wang, Xiang Wang   +17 more
doaj   +1 more source

Association of dietary inflammatory index with gynecological cancers in NHANES 2011–2018

Frontiers in Nutrition
ObjectiveThis study aimed to analyze the association between the Dietary Inflammatory Index (DII) and the risk of gynecological cancers using data collected from the National Health and Nutrition Examination Survey (NHANES) between 2011 and 2018 ...
Chen Chen, Chen Chen, Mengyu Zheng, Mengyu Zheng, Xing Dong, Xing Dong, Pei Zhang, Pei Zhang, Zhuo Bao, Zhuo Bao, Yushan Cao, Yushan Cao, Yixuan Liu, Yixuan Liu, Jinxiang Yan, Jinxiang Yan, Yongzhen Guo, Yongzhen Guo, Xianxu Zeng, Xianxu Zeng   +19 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Association of different inflammatory indices with risk of early natural menopause: a cross-sectional analysis of the NHANES 2013–2018

Frontiers in Medicine
BackgroundEarly natural menopause, characterized by the cessation of ovarian function before the age of 45, has been a subject of prior research indicating that inflammation may predict the onset of menopause.
Mengyu Zheng, Mengyu Zheng, Junying Li, Junying Li, Yushan Cao, Yushan Cao, Zhuo Bao, Zhuo Bao, Xing Dong, Xing Dong, Pei Zhang, Pei Zhang, Jinxiang Yan, Jinxiang Yan, Yixuan Liu, Yixuan Liu, Yongzhen Guo, Yongzhen Guo, Xianxu Zeng, Xianxu Zeng   +19 more
doaj   +1 more source

Adjuvant chemotherapy may improve long-term outcomes in stage IB non-small cell lung cancer patients with previous malignancies: A propensity score-matched analysis

Frontiers in Oncology, 2022
BackgroundRoutine administration of adjuvant chemotherapy for stage IB non-small cell lung cancer (NSCLC) remains controversial. To our knowledge, no available studies have assessed the outcomes of chemotherapy in patients with stage IB NSCLC who had ...
Ke Zhou, Ke Zhou, Yaqin Zhao, Linchuan Liang, Linchuan Liang, Jie Cao, Jie Cao, Huahang Lin, Huahang Lin, Zhiyu Peng, Zhiyu Peng, Jiandong Mei, Jiandong Mei   +12 more
doaj   +1 more source

The influence of social processes on the timing of cancer diagnosis: a research agenda [PDF]

, 2010
This paper sets out to review the influence of social processes on the timing of the diagnosis of cancer and to explore the potential for promoting earlier diagnosis by addressing social factors that influence symptom recognition and the diagnostic ...
Corner, Jessica L, Corner, J., L. Brindle, Brindle, L., Brindle, Lucy A, J. Corner   +5 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Pan-cancer characterization of C–C motif chemokine ligand 5 (CCL5) identifies its role as biomarker and therapeutic target

Discover Oncology
Objectives C–C Motif Chemokine Ligand 5 (CCL5) is known for its role in immune regulation and has been implicated in cancer progression. However, its expression and prognostic significance in pan-cancer require comprehensive evaluation.
Wenming Zhao, Jirui Sun, Bingjuan Zhou, Haizhi Qiao, Jinku Zhang   +4 more
doaj   +1 more source