Results 41 to 50 of about 2,379,974 (319)

THE EARLY DIAGNOSIS OF PARESIS [PDF]

open access: yesAmerican Journal of Psychiatry, 1902
It is with much hesitation that I attempt to discuss so difficult a subject as the early recognition of paresis, for here we are confronted with borderland conditions and overlapping states. I know of no subject which is so important and no subject concerning which error is more frequently made both on account of the gradual invasion and also because ...
openaire   +2 more sources

The Early Intervention Readiness Program (EIRP): A Post-ASD Diagnosis Family Support Program

open access: yes, 2017
A child’s diagnosis with autism spectrum disorder (ASD) can be an extremely stressful time for families. Researchers suggest that the period immediately following ASD diagnosis is a key time for professionals to guide families by providing appropriate ...
Bruck, Susan   +2 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Sharing information about diagnosis and outcome of firstepisode psychosis in patients presenting to early intervention services

open access: yes, 2019
AimFirst-episode psychosis (FEP) can be a serious and debilitating disease, but there is limited literature on how to inform patients and carers about its diagnosis and outcome. We aimed to examine the attitudes, practices and views of clinicians working

core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Efficacy and safety of lenvatinib plus pembrolizumab in patients with advanced and recurrent endometrial cancer: a systematic review and meta-analysis

open access: yesFrontiers in Immunology
BackgroundVarious trials have demonstrated the clinical benefits of lenvatinib plus pembrolizumab in patients with advanced or recurrent endometrial cancer, regardless of mismatch repair (MMR) status or histologic subtype.
Guangwei Yan   +15 more
doaj   +1 more source

GP Attitudes to Early Diagnosis of Dementia: Evidence of Improvement

open access: yes, 2004
This paper offers a comparative analysis of GPs attitudes towards early diagnosis of dementia in 1997 and 2001. It draws on data from two studies conducted in the same area using the same research instrument.
Milne, Alisoun   +6 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Challenges of assessing acceptability in the context of cancer screening: a behavioral science perspective

open access: yesFrontiers in Cancer Control and Society
In response to an increased focus on acceptability research in healthcare, this perspective paper highlights the challenges of assessing acceptability and the need for, and importance of, further work to develop best practice guidelines for evaluating ...
Charlotte Kelley-Jones   +9 more
doaj   +1 more source

Decreased IL-6 and NK Cells in Early-Stage Lung Adenocarcinoma Presenting as Ground-Glass Opacity

open access: yesFrontiers in Oncology, 2021
BackgroundLung ground-glass opacities (GGOs) are an early manifestation of lung adenocarcinoma. It is of great value to study the changes in the immune microenvironment of GGO to elucidate the occurrence and evolution of early lung adenocarcinoma ...
Pengfei Zhang   +22 more
doaj   +1 more source

Home - About - Disclaimer - Privacy