Results 51 to 60 of about 3,819,422 (303)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Challenges of assessing acceptability in the context of cancer screening: a behavioral science perspective

Frontiers in Cancer Control and Society
In response to an increased focus on acceptability research in healthcare, this perspective paper highlights the challenges of assessing acceptability and the need for, and importance of, further work to develop best practice guidelines for evaluating ...
Charlotte Kelley-Jones, Ninian Schmeising-Barnes, Stephanie Bonfield, Lily Taylor, Lorna McWilliams, Jo Waller, Emma Lidington, Evangelos Katsampouris, Lauren Gatting, Suzanne E. Scott   +9 more
doaj   +1 more source

TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia

Frontiers in Cell and Developmental Biology, 2022
Preeclampsia (PE) is a serious disease during pregnancy that affects approximately eight million mothers and infants worldwide each year and is closely related to abnormal trophoblast function.
Hao Wang, Hao Wang, Xiaowei Zhang, Xiaowei Zhang, Chunfeng Liu, Chunfeng Liu, Shengfu Chen, Xinyang Liu, Xinyang Liu, Shangrong Fan, Shangrong Fan   +10 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

N6-Methyladenosine RNA Methylation Regulator-Related Alternative Splicing (AS) Gene Signature Predicts Non–Small Cell Lung Cancer Prognosis

Frontiers in Molecular Biosciences, 2021
Aberrant N6-methyladenosine (m6A) RNA methylation regulatory genes and related gene alternative splicing (AS) could be used to predict the prognosis of non–small cell lung carcinoma.
Zhenyu Zhao, Zhenyu Zhao, Qidong Cai, Qidong Cai, Pengfei Zhang, Pengfei Zhang, Boxue He, Boxue He, Xiong Peng, Xiong Peng, Guangxu Tu, Guangxu Tu, Weilin Peng, Weilin Peng, Li Wang, Li Wang, Fenglei Yu, Fenglei Yu, Xiang Wang, Xiang Wang   +19 more
doaj   +1 more source

EARLY DIAGNOSIS

Paediatria Croatica, 2020
Neurometaboličke bolesti u dječjoj dobi skupina su rijetkih bolesti koja se sve više širi. Tome uvelike pridonosi dostupnost novih tehnologija koje se primjenjuju u selektivnoj laboratorijskoj dijagnostici i novorođenačkom probiru nasljednih metaboličkih poremećaja.
openaire   +1 more source

Sweet syndrome with pulmonary involvement in a patient with myelodysplastic syndrome [PDF]

, 2020
We report a patient with Sweet syndrome involving the pulmonary system in the context of myelodysplastic syndrome. Although Sweet syndrome may involve a variety of organ systems, the pulmonary system is rarely affected and can result in poor clinical ...
Bordelon, Jenna, Ho, Jonhan, James, Alaina, Karunamurthy, Arivarasan, Kazlouskaya, Viktoryia, Khosravi, Hasan, Mizes, Alicia, Patton, Timothy   +7 more
core  

Tumor markers in breast cancer - European Group on Tumor Markers recommendations [PDF]

, 2005
Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer.
Abraha RS, Andreasen PA, Arie van Dalen, ASCO Expert Panel, Barak V, Barnes DM, Baselga J, Bast RC, Benraad TH, Bieglmayer C, Blamey RW, Bonadonna G, Chan DW, Chebil G, Chu KC, Colditz G, Conneely OM, De Koning H, Devine PL, Dixon AR, Dnistrian AM, Dnistrian AM, Duffy MJ, Duffy MJ, Duffy MJ, Duffy MJ, Duffy MJ, Early Breast Cancer Trialist's, Early Breast Cancer Trialists Collaborative Group, Early Breast Cancer Trialists Collaborative Group, Easton DF, Ebeling FC, Ebeling FG, Eifel P, Einarsson R, Ekbom A, Elledge RM, Fisher B, Fitzgibbons PL, Gion M, Gion M, Guadagni F, Gyö, Harries M, Harvey JM, Helena Goike, Holli K, Holli K, Iwase H, Jager W, Jensen EV, Kamel EM, Konecny G, Kurebayashi J, Lamerz R, Leake R, Leers M, Leers MP, Leers MP, Legha SS, Leyland-Jones B, Look MP, Loomer L, Loprinzi CL, Madigan MP, Marius Nap, Massimo Gion, McCarty, McLaughlin R, Merimsky O, Michael J. Duffy, Mohsin SK, Molina R, Molina R, Molina R, Molina R, Molina R, Molina R, Molina R, Morrow M, Nakata B, Newcomb P, Nicolini A, Nicolini A, Nicolini A, O'Hanlon DM, Paik S, Palazzo S, Parker SL, Parkin DN, Pecking AP, Pertschuk LP, Pertschuk LP, Petra Stieber, Piccart MJ, Price MR, Rafael Molina, Robertson JFR, Robertson JFR, Rogers CE, Roland Einarsson, Rolf Lamerz, Romer M, Rosselli del Turco M, Safi F, Schapira DV, Schapira DV, Sjostrom J, Slamon D, Soletormos G, Soletormos G, Soletormos G, Soletormos G, Stieber P, Sturgeon CM, Sweep CGJ, Tabar L, The GIVIO, The GIVIO, Theriault RL, Thorpe SM, Tomlinson IP, Tondini C, Van Dalen A, Van Dalen A, van Dalen A, van Dalen A, Van Dalen A, van Dalen A, Veronesi U, Vivian Barak, Vizcarra E, Vyzula R, Weihua Z, Williams MR, Yamauchi H, Zucchelli GC   +136 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Intention to have blood-based multi-cancer early detection (MCED) screening among men and women aged 50–77 years from Black and Asian backgrounds: a cross-sectional survey in Great Britain

BMJ Public Health
Introduction Uptake of cancer screening is lower among people from minority ethnic groups. We aimed to quantify intention and potential barriers and facilitators to uptake of blood-based multi-cancer early detection (MCED) screening among men and women ...
Jo Waller, Laura A V Marlow, Ninian Schmeising-Barnes   +2 more
doaj   +1 more source