Results 101 to 110 of about 1,560,476 (306)

Speech-Language Outcomes in Dual-Language Learners Following Early Intervention: What About Caregiver Language?

Dual language learners are often underidentified for having language delays and may not receive services in their caregiver’s primary language. This study explored how the language used during evaluations influenced the effectiveness of a brief ...
Gonzalez, Melissa, Heymann, Perrine, Bagner, Daniel M., Natale, Ruby A.   +3 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Psychosocial Intervention: Promoting Functional Recovery in Adult Patients with Early Psychosis: A Recovery-oriented Life Coaching Intervention

, 2014
Disruptions in functioning are commonly reported in patients with psychosis. Apart from symptomatic remission, functioning is one of the most important indicators of recovery.
Lau, KMN, Chang, WC, Hui, CLM, Lee, HME, Xu, MJQ, Chen, E, Chan, SKW, Chen, EYH, Lin, JJ   +8 more
core  

Review of early childhood parenting, education and health intervention programs for Indigenous children and families in Australia [PDF]

, 2014
This paper provides a review of prevention and early intervention research literature that is focused on improving outcomes for Australian Indigenous children in the early childhood years. For the purposes of this paper, early childhood is defined as the
Jennifer Bowes, Rebekah Grace, Bowes, Jennifer, Grace, Rebekah (R19197)   +3 more
core  

Deaf and Hard of Hearing Early Intervention: Perceptions of Family-Centered Practice

, 2020
This cross-sectional quantitative study investigated parents’ perceptions of the quality of family-centered practice in an early intervention service for young children who are deaf or hard of hearing through the use of the Measures of Processes of Care (
McKee, Jen, Stewart, Victoria, Slattery, Maddy   +2 more
core   +1 more source

The Early Impact Program: An Early Intervention and Prevention Program for Children and Families At-Risk of Conduct Problems

, 2007
The Early Impact (EI) program is an early intervention and prevention program for reducing the incidence of conduct problems in pre-school aged children.
Larmar, Stephen, Gatfield, Terence John
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Early hearing detection and intervention [PDF]

Department of Health and Human Services, Centers for Disease Control and Prevention."Safer-healthier-people" --Cover.Produced by the CDC's National Center on Birth Defects and Developmental Disabilities Early Hearing Detection and Intervention Program ...

core  

Enhancing child mental health: a stepped care approach by mental health professionals at an early intervention and rehabilitation centre for children, in India

Discover Psychology
As per the Global Burden of Disease survey, in India, developmental disabilities are projected to affect more than 11 million children in the age group of less than 5 years.
Vinyas Nisarga, Prerna Khar, Henal Shah
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source