Results 101 to 110 of about 7,935,009 (305)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Sex as a moderator of the relationship between food addiction and body mass index in young non-help-seeking adults at risk for psychosis and controls

Eating and Weight Disorders
Background Obesity is one of the serious health problems among people with psychosis at the different stages. Therefore, finding effective strategies to mitigate and manage it in a timely manner before complications arise represents a big challenge for ...
Feten Fekih-Romdhane, Khouloud Akrimi, Nour Bouallègue, Majda Cheour, Souheil Hallit   +4 more
doaj   +1 more source

Format and core components of effective preventive parenting interventions for children’s emotion regulation: a protocol for an umbrella review of systematic reviews

BMJ Open
Introduction Preventive parenting interventions are a cornerstone of child mental health promotion and prevention efforts, with growing evidence supporting their overall effectiveness.
Johanne Smith-Nielsen, Katrine Røhder, Mette Skovgaard Væver, Ida Egmose, Anne Stuart, Helena-Céline Stevelt, Julie E Hansen, Jeanette B Pollmann, Nina M Lassen   +8 more
doaj   +1 more source

Early hearing detection and intervention [PDF]

Department of Health and Human Services, Centers for Disease Control and Prevention."Safer-healthier-people" --Cover.Produced by the CDC's National Center on Birth Defects and Developmental Disabilities Early Hearing Detection and Intervention Program ...

core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Speech-Language Outcomes in Dual-Language Learners Following Early Intervention: What About Caregiver Language?

Dual language learners are often underidentified for having language delays and may not receive services in their caregiver’s primary language. This study explored how the language used during evaluations influenced the effectiveness of a brief ...
Gonzalez, Melissa, Heymann, Perrine, Bagner, Daniel M., Natale, Ruby A.   +3 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Caregiver coaching in early intervention - the example of COPCA

, 2021
‘COPing with and CAring for infants with special needs’ (COPCA) is a family-centred early intervention programme.1,2 The major intervention strategy of COPCA is caregiver coaching. To understand the background of COPCA’s coaching approach it is important
Akhbari Ziegler, Schirin
core   +1 more source

PreEMPT (Preterm infant Early intervention for Movement and Participation Trial): The feasibility of a Novel, Participation-focused Early Physiotherapy intervention supported by Telehealth in Regional Australia - A Protocol

, 2020
Background: Early intervention is beneficial for improving preterm infant motor and cognitive outcomes in early childhood; however, little is known about whether early intervention can influence a preterm infant’s participation.
Johnston, Leanne, Spittle, Alicia, Mobbs, Chelsea   +2 more
core   +1 more source