Results 111 to 120 of about 1,560,476 (306)

Evaluating early intervention programmes: six common pitfalls, and how to avoid them. [PDF]

, 2018
This handy guide provides guidance on addressing six of the most common issues we see in our assessments of programme evaluations, including explanations of how these problems undermine confidence in a study’s findings, how they can be avoided or ...
Doubell, Lara, Brims, Lucy, McBride, Tim, Clarke, Aleisha, Martin, Jack, Pote, Ines   +5 more
core  

The intermediate role of impulsive personality traits between attention‐deficit/hyperactivity disorder symptoms and suicidal ideation among patients with schizophrenia

PCN Reports
Aim While there is a general consensus on Attention‐Deficit/Hyperactivity Disorder (ADHD) serving as a possible suicide risk factor in a broad range of populations, scant research has been dedicated to addressing ADHD and suicidality in schizophrenia ...
Feten Fekih‐Romdhane, Jaweher Zaouali, Ameni Barketi, Farah Ghrissi, Majda Cheour, Souheil Hallit   +5 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Early intervention for children with autism: parental priorities

, 2004
This paper describes a process of assisting parents of young children with Autistic Spectrum Disorder (ASD) to identify and prioritise their goals for their children's early intervention.
Rodger, S., Keen, Deb, Braithwaite, M.
core  

Caregiver coaching in early intervention - the example of COPCA

, 2021
‘COPing with and CAring for infants with special needs’ (COPCA) is a family-centred early intervention programme.1,2 The major intervention strategy of COPCA is caregiver coaching. To understand the background of COPCA’s coaching approach it is important
Akhbari Ziegler, Schirin
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Ethnic variations in compulsory detention and hospital admission for psychosis across four UK Early Intervention Services

, 2014
Substantial ethnic variations have been found in incidence, pathways to care and outcomes in psychosis. It is unknown whether these remain as marked in the presence of specialist Early Intervention Services (EIS) for psychosis.
Barnaby Major, Lawrence, J, Johnson, S, Joyce, John, Andrew Tapfumaneyi, Joyce, J, Fisher, Helen L; id_orcid, Jo Lawrence, Tapfumaneyi, A, Hinton, MF, Helen L Fisher, Lawrence, Jo, Hinton, Mark F, Sonia Johnson, John Joyce, Mark F Hinton, Johnson, Sonia, Fisher, HL, Mann, F, Farhana Mann, Major, Barnaby, Tapfumaneyi, Andrew, Major, B, Mann, Farhana   +23 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

4-year outcome of a specialized early intervention treatment for adult onset psychosis (JCEP): A randomized controlled trial

, 2018
Despite advances in treatment of psychotic disorders, functional decline remains a prominent obstacle in the recovery pathway. Early intervention (EI) services worldwide have focused timely treatment on the first few years (i.e.
Chang, WC, Hui, CLM, Lee, HME, Chen, EYH, Chan, KW   +4 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source