Results 31 to 40 of about 3,388,275 (347)

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Exploring the Feasibility and Acceptability of a Brief Online Dialogic Book-Sharing Training for Teaching Support Staff

Children
Background/Objectives: In the UK, significant and rising numbers of children arrive in schools with marked deficits in key skills such as oral language. This rise has been further negatively impacted by the COVID-19 pandemic.
Judy Hutchings, Rebecca Lothian, Anwen Jones, Margiad E. Williams   +3 more
doaj   +1 more source

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

An exploratory study of psychosis risk factors in individuals who are referred but do not meet criteria for an early intervention in psychosis service

BJPsych Open
Background The ‘at-risk mental state’ (ARMS) for psychosis has been critiqued for its limited prognostic ability and identification of a limited proportion of those who will develop a first episode of psychosis (FEP).
Sean Naughton, Aoife Brady, Eoin Geary, Eimear Counihan, Mary Clarke   +4 more
doaj   +1 more source

Sex-specific immune-inflammatory markers and lipoprotein profile in patients with anhedonia with unipolar and bipolar depression

BMC Psychiatry, 2023
Background Anhedonia is a core symptom in patients with unipolar and bipolar depression. However, sex-specific markers reflecting biological heterogeneity are lacking.
Shengjuan Lin, Rongxun Liu, Zhongguo Zhang, Fengyi Liu, Shisen Qin, Yange Wei, Fei Wang   +6 more
doaj   +1 more source

Effect of long-acting injectable paliperidone 3 monthly and aripiprazol 1 monthly on hospitalization rate in a first-episode psychosis

European Psychiatry, 2021
Introduction Long-acting injectable antipsychotics (LAIs) can reduce relapse and hospitalization risk but they are not widely used in first psychotic episode (FEP) patientes. Objectives To examine the effcacy of two of the most used second generation
P. Gil Lopez, J.M. Rodriguez Sanchez, L. Garcia Fernandez, V. Sanchez Estevez   +3 more
doaj   +1 more source

Financing early intervention: interim paper: Graham Allen Review [PDF]

, 2010
"This short document sets out the areas of focus for Part 2 of the review, which will report in May/June 2011. Over the next few months we will be exploring options to improve the financing of Early Intervention programmes. This will include a particular

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Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

Deciphering the Interplay Among Inflammatory Bowel Disease, Gut Microbiota, and Inflammatory Biomarkers in the Risk of Colorectal Cancer

Mediators of Inflammation
Conclusions: IBD alters the microbial abundance of Rikenellaceae RC9 gut group, Lactobacillaceae, and Ruminococcus 2, thereby, influencing inflammatory biomarkers including CRP, neutrophils, and lymphocytes, which mediate the increased risk of CRC in IBD
Chenyu Luo, Bowen Tian, Yueyang Zhou, Jiahui Luo, Qing Shang, Si Yu, Min Dai, Yue Li, Hongda Chen   +8 more
doaj   +1 more source

Parenting early intervention programme: 2nd interim report [PDF]

, 2010
Centre for Educational Development, University of ...
Cullen, Mairi Ann, Lindsay, Geoff, Strand, Steve   +2 more
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