Results 51 to 60 of about 8,229,253 (288)

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Metamorphic evolution of amphibolite from Proto-Tethys South Altyn orogen and its geological significance

open access: yesScientific Reports
Medium- to low-grade metamorphic (LP–MP) rocks, though major constituents of collisional orogens, remain less studied than high-to ultrahigh-pressure (HP–UHP) counterparts.
Shihao Zhang   +3 more
doaj   +1 more source

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash   +4 more
wiley   +1 more source

Paleoenvironmental reconstruction of the Middle Ordovician Majiagou Formation in the northeastern Ordos Basin and its effect on organic matter enrichment

open access: yesScientific Reports
The alteration of paleoenvironment is a crucial factor influencing the variations in hydrocarbon-forming organisms and the preservation of organic matter.
Yiran Wang   +4 more
doaj   +1 more source

Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright   +13 more
wiley   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Childhood Health Status and Adulthood Cardiovascular Disease Morbidity in Rural China: Are They Related? [PDF]

open access: yes, 2016
Cardiovascular diseases (CVDs) are among the top health problems of the Chinese population. Although mounting evidence suggests that early childhood health status has an enduring effect on late life chronic morbidity, no study so far has analyzed the ...
Shen, Jay, Wang, Qing
core   +3 more sources

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

An Oceanic Plateau Induced Subduction Zone Jump From Proto‐ to Paleo‐Tethys in East Kunlun, Northern Tibetan Plateau

open access: yesGeochemistry, Geophysics, Geosystems
The relationship between the Proto‐Tethys and Paleo‐Tethys is still debated. Some researchers believe that the Paleo‐Tethys opened after the Proto‐Tethys closed, while others argue that they are the same ocean with two stages of subduction.
Rutao Zang   +6 more
doaj   +1 more source

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