Results 71 to 80 of about 20,037,007 (385)

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Autism common variants associated with white matter alterations at birth: cross-sectional fixel-based analyses of 221 European term-born neonates from the developing human connectome project

open access: yesTranslational Psychiatry
Increasing lines of evidence suggest white matter (WM) structural changes associated with autism can be detected in the first year of life. Despite the condition having high heritability, the relationship between autism common genetic variants and WM ...
Hai Le   +18 more
doaj   +1 more source

Older and wiser? Men’s and women’s accounts of drinking in early mid-life [PDF]

open access: yes, 2011
Most qualitative research on alcohol focuses on younger rather than older adults. To explore older people’s relationship with alcohol, we conducted eight focus groups with 36 men and women aged 35 to 50 years in Scotland, UK.
Carstairs V.   +5 more
core   +1 more source

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez   +13 more
wiley   +1 more source

Early‐life telomere length predicts lifespan and lifetime reproductive success in a wild bird

open access: yesMolecular Ecology, 2019
Poor conditions during early development can initiate trade‐offs that favour current survival at the expense of somatic maintenance and subsequently, future reproduction.
Justin R. Eastwood   +8 more
semanticscholar   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher   +8 more
wiley   +1 more source

Was the Lhasa Block at Low Latitudes in the Middle Permian? Insights From New Paleomagnetic and Geochronological Data

open access: yesGeophysical Research Letters
The absence of reliable paleomagnetic constraints from the Lhasa Block has led to alternative interpretations of its late Paleozoic position and timing of rifting from Gondwana, reflecting uncertainties in early Neo‐Tethyan paleogeography.
Longyun Xing   +12 more
doaj   +1 more source

New reconstruction of the Wiwaxia scleritome, with data from Chengjiang juveniles

open access: yesScientific Reports, 2015
Wiwaxiids are a problematic group of scale-covered lophotrochozoans known from Cambrian Stages 3–5. Their imbricating dorsal scleritome of leaf-like scales has prompted comparison with various annelids and molluscs and has been used as a template to ...
Zhifei Zhang, Martin R. Smith, Degan Shu
doaj   +1 more source

Association of Maternal Neurodevelopmental Risk Alleles With Early-Life Exposures

open access: yesJAMA psychiatry, 2019
Key Points Question Are maternal polygenic risk scores for neurodevelopmental disorders associated with early-life exposures? Findings In this population-based cohort study of 7921 mothers, polygenic risk score for attention-deficit/hyperactivity ...
Beate Leppert   +9 more
semanticscholar   +1 more source

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