Results 61 to 70 of about 541,912 (259)

Clinical Evaluation of Early Loaded and Unloaded Implants in Edentulous Mandible [PDF]

Journal of Maxillofacial and Oral Surgery, 2011
The aim of this study is to compare and evaluate the clinical outcome of early loaded and unloaded implants in the interforaminal region of anterior mandible.Five completely edentulous patients aged between 45 and 65 years were selected satisfying certain criteria.
S, Anil Kumar, Nandkishore, Sahoo, V, Radhakrishnan, H S, Sandhu   +3 more
openaire   +2 more sources

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A sensitive test for early myocardial iron loading [PDF]

European Heart Journal, 2003
See doi:10.1016/S1095-668X(02)00381-0for the article to which this editorial refers. A third of patients born with thalassaemia major in the UK die, usually from iron-induced cardiomyopathy by the age of 35.1 Daily subcutaneous infusions of the iron-chelating drug desferrioxamine have been used since 1976 to prevent iron-induced organ damage ...
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigation of the expression of the C-terminal cross-linking telopeptide of type I collagen (CTXI) in saliva during early and delayed loading of dental implants

BMC Oral Health
Background Implants are commonly used as a treatment choice for partially dentate or edentulous patients. Currently, no specific biomarker for assessing the bone status around dental implants of healthy patients has been reported for evaluating bone ...
Dania Hamid, Shaheen Ahmed, Abdul Hafeez Shaikh, Sadaf Nisar, Raheel Memon, Samreen Malik   +5 more
doaj   +1 more source

Prediction of biomechanical complications in patients with implant supported fixed dental prostheses in different terms of functional loading

Zaporožskij Medicinskij Žurnal, 2017
Objective – to study features of biomechanical complications (structural fractures, loss of retention, screw loosening/fracture) of implant restorations in different terms of functional loading and work out preventive measures.
O. M. Doroshenko, O. F. Sirenko
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Review of Immediate and Early Loading Protocols in Dental Implants

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2010
Introduction: The concept of treating edentulous patients by osseointegrated implants was first proposed in 1960s. To minimize the failure rate of implants, it has been recommended to keep the implants free of load during the healing period .Recent ...
M Rismanchian, N Khodaeian, E Ataei
doaj