Results 71 to 80 of about 541,912 (259)

Immediate Loading of Post-Extraction Implants: Success and Survival Rates: A Systematic Review and Meta-Analysis

open access: yesApplied Sciences
The study aimed to assess the success and survival rates of post-extraction implants with immediate loading. A systematic search was performed in the Medline (PubMed), Cochrane Library (Wiley), and Scopus (Elsevier) databases to identify randomized and ...
Pastora del Pilar Rojas-Rojas   +5 more
doaj   +1 more source

DIC-aided biaxial fatigue tests of a 304L steel

open access: yesEPJ Web of Conferences, 2010
Several biaxial fatigue tests are conducted up to 106 cycles at room temperature in the context of a collaboration LMT-Cachan / EDF / AREVA / SNECMA / CEA. Malteses cross specimens of 304L steel, designed to initiate crack in the bulk, are loaded by a
Le-Roux J.C.   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Allostatic load in early pregnancy and sleep-disordered breathing

open access: yesThe Journal of Maternal-Fetal & Neonatal Medicine
To assess the association between allostatic load in early pregnancy and sleep-disordered breathing (SDB) during pregnancy. High allostatic load in the first trimester was defined as ≥ 4 of 12 biomarkers (systolic blood pressure, diastolic blood pressure, body mass index, cholesterol, low-density lipoprotein, high-density lipoprotein, high sensitivity ...
Amir J, Lueth   +8 more
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Effects of immediate loading directionality on the mechanical sensing protein PIEZO1 expression and early-stage healing process of peri-implant bone

open access: yesBioMedical Engineering OnLine
Background The reduced treatment time of dental implants with immediate loading protocol is an appealing solution for dentists and patients. However, there remains a significant risk of early peri-implant bone response following the placement of ...
Chuanyuan Mao   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Mechanical Behavior Evolution and Damage Characterization of Coal under Different Cyclic Engineering Loading

open access: yesGeofluids, 2020
The cyclic loading causes the strength change of porous rocks, which can be frequently encountered in underground coal mining. In order to quantify the cumulative damage of porous coal, multilevel uniaxial cyclic compressive tests were carried out ...
Huajun Wang, Jian Li
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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