Results 91 to 100 of about 30,157 (379)

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Working in the Dark? Exploring the Relationship Between the Dark Triad and Early Maladaptive Schemas

Trends in Psychology
Early maladaptive schemas (EMS) may contribute to the Dark Triad’s (i.e., Machiavellianism, narcissism, psychopathy) dysfunctional workplace outcomes.
Simone Judith Ray, Katerina Fritzon
semanticscholar   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

The mediating role of cognitive emotion regulation strategies and social self-efficacy in the relationship between early maladaptive schemas and social anxiety in adolescent girls

مجله علوم روانشناختی, 2021
Background: Social anxiety is one of the factors that disrupts the process of social development in individuals. Numerous studies have confirmed the relationship between early maladaptive schemas and social anxiety, but the key question is whether ...
Seddigheh Kouchi, Shahram Mami, Vahid Ahmadi   +2 more
doaj  

The Relationship between Early Maladaptive Schemas with Clinical Personality Patterns in Prisoners having Personality Disorders [PDF]

, 2017
This study aimed to investigate the relationship between early maladaptive schemas with clinical personality patterns in prisoners having personality disorder The study population consisted of male prisoners in Behshahr city The total of 80 male ...
Sakineh Valian
core   +1 more source

Early maladaptive schemas and borderline personality disorder features in a nonclinical sample : a network analysis [PDF]

, 2019
Borderline personality disorder (BPD) is a challenging problem. Early maladaptive schemas (EMSs) are considered as important vulnerability factors for the development and maintenance of BPD. Literature suggests a complex relationship between BPD and EMSs.
Ahi G. H., Arntz A., Frias A., Glaser B. A., Linehan M. M., Mojallal M., Morey L. C., Young J. E., Young J. E., Young J. E.   +9 more
core   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Predicting psychological need satisfaction and frustration from early maladaptive schemas and DSM-5 and ICD-11 personality traits

Current Psychology
The satisfaction of basic psychological needs is closely connected with an individual’s well-being and mental health. The purpose of the present study was to examine the associations of persistent and pervasive negative cognitions about oneself and ...
J. Thimm
semanticscholar   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Relationship Between Early Maladaptive Schemas, COVID-19 Anxiety, and Death Anxiety During COVID-19 Pandemic

Health Scope
Background: The COVID-19 pandemic led to significant concerns and public panic. Due to the ambiguous and deadly nature of this virus, it triggers anxiety related to COVID-19 and a fear of death.
Mohammad Davood Mohebi, Jafar Sarani Yaztappeh, Zahra Nazarali, Saina Fatollahzadeh, Behzad Rigi Kooteh   +4 more
semanticscholar   +1 more source