Results 81 to 90 of about 4,392 (296)

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

BMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song, Yunlong Wu, Xing Chen, Yafei Liu, Mengna Dong, Jiawei Shi, Xichi Wang, Nianguo Dong, Weihua Qiao, Qin Wang   +9 more
wiley   +1 more source

The path analysis of early maladaptive schemas, coping strategies and mental quality of life

, 2014
Aim and Background: Early maladaptive schemas are assumed to be a disrupting factor for quality of life. Yet, the mechanism of this vulnerability is not well known. The purpose of this study was to investigate mediating effect of coping strategies on the
Izadikhah, Zahra, Nasab, Maryam, Dehghani, Sepideh, Rezaei, Elham   +3 more
core  

Long‐lasting remodeling of astrocytes in an Scna1+/− mouse model of Dravet syndrome

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a prototypical developmental and epileptic encephalopathy caused by mutations in the SCN1A gene, leading to loss of function of the voltage‐gated sodium channel Naᵥ1.1. The latter causes early onset drug‐resistant seizures and enduring cognitive and behavioral deficits.
Athénaïs Genin, Alicia Janvier, Tristan Moujellil‐Legagneur, Marine Blaquière, Alexis Chaussy, Romane Privé, Fabrice Duprat, Massimo Mantegazza, Etienne Audinat, Nicola Marchi, Noémie Cresto   +10 more
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

The relationship between early maladaptive schemas with marital satisfaction and psychological distress in infertile women in tehran

مجله علوم روانشناختی, 2020
Background: Numerous studies have examined early maladaptive schemas and marital satisfaction and psychological distress. But there is research on the relationship between early maladaptive schemas and marital satisfaction and the psychological distress ...
abdolbast mahmoudpour, mohammad darba, zahra kamandloo, yaser madani   +3 more
doaj  

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Role of Early Maladaptive Schemas on Addiction Potential in Youth

International Journal of High Risk Behaviors and Addiction, 2013
Drug abuse in juveniles is one of the most serious problems which lead to different physical, social and educational damages and outcomes.The aim of the present study is to predict the addiction Potential in youths by their early maladaptive schemas.The research sample included students of the University of Sistan and Baluchistan, Zahedan, Iran, with ...
Bakhshi Bojed, Fereshteh, Nikmanesh, Zahra   +1 more
openaire   +3 more sources

Using Virtual Reality Social Environments to Promote Outcomes' Generalization of AVATAR Therapy for Distressing Voices: A Case Study

Journal of Clinical Psychology, Volume 81, Issue 6, Page 516-525, June 2025.
ABSTRACT AVATAR therapy (AT) works by facilitating a ‘face‐to‐face’ dialog between the person and a digital representation (avatar) of their persecutory voice. Although there is cumulative evidence of this way of working with voices, enhancing the therapeutic focus on improved confidence and a sense of control of the voices in social situations ...
Mar Rus‐Calafell, Nils Ehrbar, Tobias Teismann, Silvia Schneider, Ekincan Tas, Simon Schuster, Clementine Edwards, Mark Huckvale, Thomas Craig, Philippa Garety, Thomas Ward   +10 more
wiley   +1 more source

Maladaptive Cognitive Schemas as Predictors of Disordered Eating: Examining the Indirect Pathway through Emotion Regulation Difficulties

, 2022
eating patterns. Moreover, no prior study has considered the potential role of difficulties in negative emotion regulation when disentangling the complex correlations between early maladaptive schemas and disturbed eating habits.
Obeid, Sahar, Gerges, Sarah, Malaeb, Diana, Hallit, Souheil   +3 more
core   +1 more source