Results 61 to 70 of about 30,157 (379)

A History of Trauma is Associated with Aggression, Depression, Non-Suicidal Self-Injury Behavior, and Suicide Ideation in First-Episode Psychosis. [PDF]

, 2019
The association between trauma and psychosis outcomes is well-established, and yet the impact of trauma on comorbid clinical symptoms-such as aggression, non-suicidal self-injury behavior (NSSIB), suicide ideation, and suicide behavior-for those with ...
Botello, Renata M, Carter, Cameron S, Grattan, Rebecca E, Lara, Natalia, Maguire, Adrienne M, Niendam, Tara A, Tryon, Valerie L   +6 more
core   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Parental Bonding and Early Maladaptive Schemas [PDF]

Journal of Psychological Abnormalities in Children, 2013
Objective:Attachment bonds are present throughout one’s life and affect interpersonal relationships. Specifically, parent-child relationship is a key factor in the development of personality. Similarly, childhood experiences can lead to configuration and stabilization of cognitive patterns, which play an equally important role in the development and
openaire   +1 more source

Early Maladaptive Schemas among children: a new way to screen for depressed child [PDF]

, 2013
How can children’s schemas evolve into adult schemas that are responsible for depression? To answer this question, we translated Schmidt, Joiner, Young, and Telch’s (1995) Early Maladaptive Schema Questionnaire into French and adapted it to children.
A.H. Boudoukha, D. Dafonseca, E. Charbonnier, P. Graziani, S. Rusinek   +4 more
core   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Promoting Emotion and Behavior Regulation in Male Prison Inmates: A Secondary Data Analysis From a Randomized Controlled Trial Testing the Efficacy of the Growing Pro-Social Program [PDF]

, 2017
This article describes a secondary data analysis collected from inmates who participated in an independent randomized controlled trial, testing the efficacy of the Growing Pro-Social (GPS) Program. The current study aimed to test the program's ability to
Brazão, Nélio, Pinto-Gouveia, José, Rijo, Daniel, Salvador, Maria do Céu   +3 more
core   +1 more source

Early Maladaptive Schemas and Online Pornography Use: A Cross-Sectional Study

International Journal of Mental Health and Addiction
Several studies have explored the relationship between early maladaptive schemas and mental health difficulties, including behavioural addictions. However, no empirical studies have examined the relationship between early maladaptive schemas (EMSs) and
Claudio Vieira, D. Kuss, M. D. Griffiths
semanticscholar   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

The Moderating Role of Lifestyle on Maladaptive Schemas and Responsibility among Iranian Male Teachers [PDF]

, 2018
Introduction: Responsibility can be affected by personality and life conditions. The present study was conducted to investigate the moderating role of lifestyle on maladaptive schemas and responsibility among Iranian male teachers.
Amani, Malahat
core   +2 more sources

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source