Results 81 to 90 of about 30,157 (379)
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li +11 more
wiley +1 more source
Anger and assaultiveness of male forensic patients with developmental disabilities : links to volatile parents [PDF]
This study with 107 male forensic patients with developmental disabilities investigated whether exposure to parental anger and aggression was related to anger and assaultiveness in a hospital, controlling for background variables.
Novaco, Raymond, Taylor, John
core +1 more source
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li +14 more
wiley +1 more source
Plain English Summary This study examined the relationship between early maladaptive schemas, temperament, eating attitude and the effect of gender variable on these concepts in adults.
Kahraman Güler, Zeynep Özgörüş
doaj +1 more source
Cognitive-Behavioral Therapy [PDF]
Cognitive-behavioral therapy (CBT) is the merging of behavioral and cognitive therapies that mostly focuses on working with the client in the present. Although there are many approaches to CBT, there tend to be some common features.
Rice, Robert H.
core +1 more source
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia +13 more
wiley +1 more source
Background: Attachment styles, early maladaptive schemas and defense mechanisms are the major determinants of psychological problems. Discovering the relationships of these variables has theoretical and clinical importance.
Mohammad Ali Besharat +2 more
doaj
Relations between God-Images and Early Maladaptive Schemas.
Our God image not only determines the nature of our relationship with God, it also influences our personality, actions, self-concept, mindset and social relations. It acts within and through us. Although everyone has a God image - regardless of whether one is a believer or not - the ways in which we experience God's relation to us are manifold.
Ferenczi, Andrea +2 more
openaire +2 more sources
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang +10 more
wiley +1 more source
A Comparison of Early Maladaptive Schemas in Crystal Addicted Individuals and Normal Individuals
Objective: The aim of present research was to compare early maladaptive schemas in crystal addicted individuals and normal individuals. Method: In this ex post facto research, two groups of subjects (normal adolescent=30 and addicted adolescent=30) were ...
Zahra Asadi +2 more
doaj

