Results 131 to 140 of about 299,641 (309)

The selected issues of the early middle-ages burial places [PDF]

open access: yes, 2008
I. Introduction. The dissertation paper contains four separate studies dealing with the topíc ofburials in the Early Middle-Ages. The paper's focus is the Czech Early Middle-Ages environment, however, in all studies the author tried to integrate the ...
Štefan, Ivo
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Searching for Dubh: Experiments in Black Dyes Pre 15th Century in Ireland and Scotland

open access: yesEXARC Journal
This paper explores sources of black dyes in Ireland and Scotland prior to 1500, in order to better understand the extent to which they were used and the hues that can be produced.
Ashley Stillwell-Hasan
doaj  

Бронзов медальон от Велики Преслав

open access: yesПриноси към българската археология, 2018
This article presents a pendant discovered during the archaeological excavations at a site named “Street“, situated to the south of the Bishop’s Residence.
Zhivko Aladzhov
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Ages on weathered Plio-Pleistocene tephra sequences, western North Island, New Zealand

open access: yes, 2001
Using the zircon fission-track method, we have obtained five ages on members of two strongly-weathered silicic, Pliocene-Pleistocene tephra sequences, the Kauroa and Hamilton Ash formations, in western North Island, New Zealand.
Liddell, Ivan J.   +5 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Conference Review: EXARC at the International Congress on Medieval Studies in Kalamazoo, Michigan (USA)

open access: yesEXARC Journal, 2017
The International Congress on Medieval Studies is held at Western Michigan University in Kalamazoo each May. Now in its 52nd year, ICMS draws around 3,000 people attending approximately 575 sessions of papers, panel discussions, round tables, workshops ...
Neil Peterson, Karen Davidson
doaj  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Thefts of Relics in Italy: From Late Antiquity to the Central Middle Ages, 300–1150

open access: yes
With the birth of the cult of the saints, their relics became valuables whose possession would guarantee prestige, protection, and spiritual benefits to a town, church, or monastery. For this reason—at first with the aim of preserving the bodies of newly-
Papasidero, Marco
core   +1 more source

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