Results 111 to 120 of about 6,792,361 (251)
Changes in Scale in the Italian Countryside from Late Antiquity to the Early Middle Ages
, 2011 Even if in Italy there is a tendence to emphasize a continuity between the Late Antique era and the Early Medieval Ages, we cannot deny that a radical break took place (on a quantitative as well as a qualitative scale) between the 5th and the 7th ...
CHAVARRIA ARNAU, ALEJANDRA +1 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
, 2011 This review of Chris Wickham's Framing the Early Middle Ages situates the book within the context of his earlier writings on the transition to feudalism, and contrasts his explanation for and dating of the process with those of the two main opposing ...
Davidson, Neil
core
Searching for Dubh: Experiments in Black Dyes Pre 15th Century in Ireland and Scotland
EXARC JournalThis paper explores sources of black dyes in Ireland and Scotland prior to 1500, in order to better understand the extent to which they were used and the hues that can be produced.
Ashley Stillwell-Hasan
doaj
Бронзов медальон от Велики Преслав
Приноси към българската археология, 2018 This article presents a pendant discovered during the archaeological excavations at a site named “Street“, situated to the south of the Bishop’s Residence.
Zhivko Aladzhov
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
The Middle Ages in the Modern Game: Representing the Play Element of Historical Cultures
, 2017 The representation of the Middle Ages and associated themes in videogames continues to draw academic interest (e.g. Kline 2014). Generally analytical approaches to historical representation in videogames concentrate on the inclusion and negotiation of ...
Chapman, Adam,
core
Hypereutectoid steel in early medieval sword production in Europe
Fasciculi Archaeologiae Historicae, 2014 Hypereutectoid steel is viewed as a material of exceeding quality for the manufacture of swords, providing keen edges and strong bodies to their blades.
Paweł Kucypera, Jiří Hošek
doaj