Results 101 to 110 of about 6,792,361 (251)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

The Modern Devout and `Private' Religion

open access: yes, 2006
Lecture held April 6, 2006, 7 p.m. in Woodward Hall, UNM as the final lecture of the Institute for Medieval Studies' Spring Lecture Series 2006.The influential and innovative religious movement known as the Devotio Moderna or "Modern Devotion" first ...
Van Engen, John H.
core  

Vertèbres d’un ange de mer

open access: yesArchéopages, 2023
Stéphane Augry
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Emotion, violence, vengeance and law in the Middle Ages : essays in honour of William Ian Miller /

open access: yes, 2018
Emotion, violence, vengeance, and law in Medieval Historical Sources -- Hot anger and just indignation: Justificatory strategies in Early Modern German homicide trials / Susanne Pohl-Zucker -- Trial by ordeal by jury in Medieval England, or Saints and ...
Gilbert, Kate,edt   +1 more
core  

English and Galician in the Middle Ages : a sociohistorical survey

open access: yes, 2004
The sociohistorical approach provides a most accurate framework for the comparative study of both the English and the Galician speech communities in the Middle Ages.
Crespo García, Begoña
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

The Lindisfarne Gospels: The Transforming Power of Sacred Text

open access: yes, 2006
Lecture held April 4, 2006, 4 p.m. in Woodward Hall, UNM as the second lecture of the Institute for Medieval Studies' Spring Lecture Series 2006.Of all forms of human knowledge, sacred texts may seem to be the least open to change over time.
Brown, Michelle P.
core  

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