Results 81 to 90 of about 6,792,361 (251)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Christendom and christianity in the middle ages

, 1993
Though buffetted on all sides by rapid and at times cataclysmic social, political, and economic change, the medieval church was able to make adjustments that kept it from becoming simply a fossil from the past rather than an enduring institution of ...
Bruinsma, Reinder, Bredero, Adriaan H.
core  

International Learning Partnership: Living History and Adult Education in the Museum

EXARC Journal, 2012
Many archaeological open-air museums and museums with indoor reconstructions choose to interpret history using the method of ‘living history’, or re-enactments. If one only counts the German references, there is wide variety of terms used by museums when
Susanne Wiermann
doaj  

Os agentes públicos e a fome nos primeiros séculos da Idade Média

Varia História
Resumo A Alta Idade Média foi um período marcado por sucessivas crises alimentares. De acordo com um levantamento nas histórias, anais, crônicas, hagiografias etc., feito no início do século XX pelo historiador alemão Fritz Curschmann, há 68 menções a ...
Marcelo Cândido da Silva
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Interpreting Transformations of People and Landscapes in Late Antiquity and the Early Middle Ages. Archaeological Approaches and Issues

, 2018
In this volume of papers, deriving from two conferences held in Rome and Leicester in 2016, nineteen leading European archaeologists discuss and interpret the complex evolution of landscapes – both urban and rural – across Late Antiquity and the Early ...
Seaman, Andy, Brogiolo, Gian Pietro, Meneghini, Roberto, Vigil-Escalera Guirado, Alfonso, Chavarría Arnau, Alexandra, Raynaud, Claude, Esmonde Cleary, Simon, Collins, Rob, Diarte-Blasco, Pilar, Heeren, Stijn, Arce, Javier, Christie, Neil, Goffredo, Roberto, Ariño, Enrique, Tompkins, Abigail E. I., Olmo Enciso, Lauro, Volpe, Giuliano, Rippon, Stephen, White, Roger   +18 more
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